Anti-TFPT Antibody (CAB6461)
- SKU:
- CAB6461
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Antibody Name: | Anti-TFPT Antibody |
Antibody SKU: | CAB6461 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TFPT (NP_037474.1). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TFPT (NP_037474.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MELE QREG TMAA VGFE EFSA PPGS ELAL PPLF GGHI LESE LETE VEFV SGGL GGSG LRER DEEE EAAR GRRR RQRE LNRR KYQA LGRR CREI EQVN ERVL NRLH QVQR ITRR LQQE RRFL MRVL DSYG DDYR ASQF TIVL EDEG SQGT DAPT PGNA ENEP PEKE TLSP PRRT PAPP EPGS PAPG EGPS GRKR RRVP RDGR RAGN ALTP ELAP VQIK VEED FGFE ADEA LDSS WVSR GPDK LLPY PTLA SPAS D |
Gene ID: | 29844 |
Uniprot: | P0C1Z6 |
Cellular Location: | Nucleus |
Calculated MW: | 27kDa/28kDa |
Observed MW: | Refer to Figures |
Synonyms: | TFPT, FB1, INO80F, amida |
Background: |
UniProt Protein Function: | TFPT: forms a fusion protein with E2A via translocation in childhood pre-B ALL. Overexpression of TFPT induces apoptosis. Causes cell cycle inhibition in the S-phase and blocks entry into mitosis. Interacts with Cdc2 in mitosis and overexpression decreases Cdc2 activity. |
UniProt Protein Details: | Protein type:Apoptosis; Oncoprotein Chromosomal Location of Human Ortholog: 19q13 Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; nucleolus; actin filament; nucleus Molecular Function:protein binding; DNA binding; protein heterodimerization activity; protein kinase binding Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of apoptosis; DNA repair; DNA recombination |
UniProt Code: | P0C1Z6 |
NCBI GenInfo Identifier: | 126352246 |
NCBI Gene ID: | 29844 |
NCBI Accession: | P0C1Z6.1 |
UniProt Related Accession: | P0C1Z6 |
Molecular Weight: | 253 |
NCBI Full Name: | TCF3 fusion partner |
NCBI Synonym Full Names: | TCF3 (E2A) fusion partner (in childhood Leukemia) |
NCBI Official Symbol: | TFPT |
NCBI Official Synonym Symbols: | FB1; amida; INO80F |
NCBI Protein Information: | TCF3 fusion partner; INO80 complex subunit F; amida, partner of the E2A |
UniProt Protein Name: | TCF3 fusion partner |
UniProt Synonym Protein Names: | INO80 complex subunit F; Protein FB1 |
Protein Family: | TCF3 fusion partner |
UniProt Gene Name: | TFPT |
UniProt Entry Name: | TFPT_HUMAN |