Anti-TENM1 Antibody (CAB15774)
- SKU:
- CAB15774
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-TENM1 Antibody |
| Antibody SKU: | CAB15774 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human TENM1 (NP_001156750.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, U-251MG, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human TENM1 (NP_001156750.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QPVE GELY ANGV SKGN RGTE SMDT TYSP IGGK VSDK SEKK VFQK GRAI DTGE VDIG AQVM QTIP PGLF WRFQ ITIH HPIY LKFN ISLA KDSL LGIY GRRN IPPT HTQF DFVK LMDG KQLV KQDS KGSD DTQH SPRN LILT SLQE TGFI EYMD QGPW YLAF YNDG KKME QVFV LTTA IEIM DDCS TNCN GNG |
| Gene ID: | 10178 |
| Uniprot: | Q9UKZ4 |
| Cellular Location: | Cell membrane, Cytoplasm, Nucleus, Nucleus matrix, Nucleus speckle, Single-pass membrane protein, cytoskeleton |
| Calculated MW: | 305kDa |
| Observed MW: | 280kDa |
| Synonyms: | TENM1, ODZ1, ODZ3, TEN-M1, TNM, TNM1 |
| Background: | The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | ODZ1: May function as a cellular signal transducer. Belongs to the tenascin family. Teneurin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: Xq25 Cellular Component: cytoplasm; cytoskeleton; endoplasmic reticulum; extracellular region; Golgi apparatus; integral to plasma membrane; nuclear matrix; nuclear speck; nucleus; perinuclear region of cytoplasm; plasma membrane Molecular Function:heparin binding; protein heterodimerization activity; protein homodimerization activity Biological Process: immune response; negative regulation of cell proliferation; nervous system development; neuropeptide signaling pathway; positive regulation of actin filament polymerization; positive regulation of filopodium formation; positive regulation of MAP kinase activity; positive regulation of peptidyl-serine phosphorylation; regulation of transcription from RNA polymerase III promoter; transcription, DNA-dependent |
| NCBI Summary: | The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| UniProt Code: | Q9UKZ4 |
| NCBI GenInfo Identifier: | 110347400 |
| NCBI Gene ID: | 10178 |
| NCBI Accession: | NP_055068.2 |
| UniProt Secondary Accession: | Q9UKZ4,Q5JZ17, B2RTR5, |
| UniProt Related Accession: | Q9UKZ4 |
| Molecular Weight: | 305,947 Da |
| NCBI Full Name: | teneurin-1 isoform 3 |
| NCBI Synonym Full Names: | teneurin transmembrane protein 1 |
| NCBI Official Symbol: | TENM1 |
| NCBI Official Synonym Symbols: | TNM; ODZ1; ODZ3; TNM1; TEN-M1 |
| NCBI Protein Information: | teneurin-1 |
| UniProt Protein Name: | Teneurin-1 |
| UniProt Synonym Protein Names: | Protein Odd Oz/ten-m homolog 1; Tenascin-M1; Ten-m1 |
| UniProt Gene Name: | TENM1 |
| UniProt Entry Name: | TEN1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TENM1 antibody (CAB15774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of C6 cells using TENM1 antibody (CAB15774) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of L929 cells using TENM1 antibody (CAB15774) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of U-2 OS cells using TENM1 antibody (CAB15774) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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