Anti-TBC1D1 Antibody (CAB9501)
- SKU:
- CAB9501
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-TBC1D1 Antibody |
| Antibody SKU: | CAB9501 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-710 of human TBC1D1 (NP_055988.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-710 of human TBC1D1 (NP_055988.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GLQE HSIS VDLD SSLS STLS NTSK EPSV CEKE ALPI SESS FKLL GSSE DLSS DSES HLPE EPAP LSPQ QAFR RRAN TLSH FPIE CQEP PQPA RGSP GVSQ RKLM RYHS VSTE TPHE RKDF ESKA NHLG DSGG TPVK TRRH SWRQ QIFL RVAT PQKA CDSS SRYE DYSE LGEL PPRS PLEP VCED GPFG PPP |
| Gene ID: | 23216 |
| Uniprot: | Q86TI0 |
| Cellular Location: | Nucleus |
| Calculated MW: | 131kDa/133kDa |
| Observed MW: | 133kDa |
| Synonyms: | TBC1D1, TBC, TBC1 |
| Background: |
| UniProt Protein Function: | TBC1D1: a putative GTPase activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. |
| UniProt Protein Details: | Protein type:GAPs; Ubiquitin-specific protease; GAPs, Rab Chromosomal Location of Human Ortholog: 4p14 Cellular Component: cytosol; endomembrane system; intracellular Molecular Function:GTPase activator activity; protein binding; Rab GTPase binding Biological Process: intracellular protein transport; regulation of vesicle fusion |
| NCBI Summary: | TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q86TI0 |
| NCBI GenInfo Identifier: | 116242816 |
| NCBI Gene ID: | 23216 |
| NCBI Accession: | Q86TI0.2 |
| UniProt Secondary Accession: | Q86TI0,Q96K82, Q9UPP4, B7Z3D9, E9PGH8, |
| UniProt Related Accession: | Q86TI0 |
| Molecular Weight: | 131,378 Da |
| NCBI Full Name: | TBC1 domain family member 1 |
| NCBI Synonym Full Names: | TBC1 domain family member 1 |
| NCBI Official Symbol: | TBC1D1 |
| NCBI Official Synonym Symbols: | TBC; TBC1 |
| NCBI Protein Information: | TBC1 domain family member 1 |
| UniProt Protein Name: | TBC1 domain family member 1 |
| Protein Family: | TBC1 domain family |
| UniProt Gene Name: | TBC1D1 |
| UniProt Entry Name: | TBCD1_HUMAN |
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