Anti-TAF3 Antibody (CAB17358)
- SKU:
- CAB17358
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-TAF3 Antibody |
| Antibody SKU: | CAB17358 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human TAF3. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | K-562, HeLa, mouse spleen, mouse brain, rat brain |
| Immunogen: | Recombinant protein of human TAF3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 83860 |
| Uniprot: | Q5VWG9 |
| Cellular Location: | |
| Calculated MW: | 103kDa |
| Observed MW: | 80kDa/140kDa |
| Synonyms: | TAF140, TAFII140, TAFII-140, TAF3 |
| Background: | The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors. |
| UniProt Protein Function: | TAF140: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process. Belongs to the TAF3 family. |
| UniProt Protein Details: | Protein type:Transcription initiation complex Chromosomal Location of Human Ortholog: 10p15.1 Cellular Component: nucleoplasm; nucleus; transcription factor TFIID complex Molecular Function:protein binding Biological Process: maintenance of protein localization in nucleus; negative regulation of transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter |
| NCBI Summary: | The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009] |
| UniProt Code: | Q5VWG9 |
| NCBI GenInfo Identifier: | 74747393 |
| NCBI Gene ID: | 83860 |
| NCBI Accession: | Q5VWG9.1 |
| UniProt Secondary Accession: | Q5VWG9,Q05DA0, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8 |
| UniProt Related Accession: | Q5VWG9 |
| Molecular Weight: | 103,582 Da |
| NCBI Full Name: | Transcription initiation factor TFIID subunit 3 |
| NCBI Synonym Full Names: | TATA-box binding protein associated factor 3 |
| NCBI Official Symbol: | TAF3 |
| NCBI Official Synonym Symbols: | TAF140; TAFII140; TAFII-140 |
| NCBI Protein Information: | transcription initiation factor TFIID subunit 3 |
| UniProt Protein Name: | Transcription initiation factor TFIID subunit 3 |
| UniProt Synonym Protein Names: | 140 kDa TATA box-binding protein-associated factor; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; TAF(II)140; TAF140; TAFII-140; TAFII140 |
| Protein Family: | Transcription initiation factor |
| UniProt Gene Name: | TAF3 |
| UniProt Entry Name: | TAF3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TAF3 antibody (CAB17358) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min. |
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