Anti-SUN1 Antibody (CAB16024)
- SKU:
- CAB16024
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-SUN1 Antibody |
| Antibody SKU: | CAB16024 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-278 of human SUN1 (NP_001165416.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-278 of human SUN1 (NP_001165416.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MYSP PQCV PENT GYTY ALSS SYSS DALD FETE HKLD PVFD SPRM SRRS LRLA TTAC TLGD GEAV GADS GTSS AVSL KNRA ARTT KQRR STNK SAFS INHV SRQV TSSG VSHG GTVS LQDA VTRR PPVL DESW IREQ TTVD HFWG LDDD GDLK GGNK AAIQ GNGD VGAA AATA HNGF SCSN CSML SERK DVLT AHPA APGP VSRV YSRD RNQK CKSQ SFKT QKKV CFPN LIFP FCKS QCLH YLSW RLKI IP |
| Gene ID: | 23353 |
| Uniprot: | O94901 |
| Cellular Location: | |
| Calculated MW: | 90kDa |
| Observed MW: | 90kDa |
| Synonyms: | SUN1, UNC84A |
| Background: | This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | SUN1: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non- coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs). 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cytoskeletal Chromosomal Location of Human Ortholog: 7p22.3 Cellular Component: nuclear membrane; intracellular membrane-bound organelle; integral to nuclear inner membrane; nuclear envelope; acrosomal membrane Molecular Function:protein binding; lamin binding Biological Process: nuclear membrane organization and biogenesis |
| NCBI Summary: | This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2010] |
| UniProt Code: | O94901 |
| NCBI GenInfo Identifier: | 195972890 |
| NCBI Gene ID: | 23353 |
| NCBI Accession: | NP_001124437.1 |
| UniProt Secondary Accession: | O94901,Q96CZ7, Q9HA14, Q9UH98, A5PL20, B3KMV7, B4DZF7 B7WNY4, B7WP53, E9PDU4, E9PF23, F8WD13, |
| UniProt Related Accession: | O94901 |
| Molecular Weight: | 101,932 Da |
| NCBI Full Name: | SUN domain-containing protein 1 isoform a |
| NCBI Synonym Full Names: | Sad1 and UNC84 domain containing 1 |
| NCBI Official Symbol: | SUN1 |
| NCBI Official Synonym Symbols: | UNC84A |
| NCBI Protein Information: | SUN domain-containing protein 1 |
| UniProt Protein Name: | SUN domain-containing protein 1 |
| UniProt Synonym Protein Names: | Protein unc-84 homolog A; Sad1/unc-84 protein-like 1 |
| Protein Family: | Secreted beta-glucosidase |
| UniProt Gene Name: | SUN1 |
| UniProt Entry Name: | SUN1_HUMAN |
 | Western blot analysis of extracts of mouse testis, using SUN1 antibody (CAB16024) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
Anti-VASH1 Antibody (CAB12569)
Anti-GLYAT Antibody (CAB14100)
