Anti-SULT1A2 Antibody (CAB12851)
- SKU:
- CAB12851
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-SULT1A2 Antibody |
| Antibody SKU: | CAB12851 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-295 of human SULT1A2 (NP_001045.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-431, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-295 of human SULT1A2 (NP_001045.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KREI QKIL EFVG RSLP EETV DLMV EHTS FKEM KKNP MTNY TTVR REFM DHSI SPFM RKGM AGDW KTTF TVAQ NERF DADY AEKM AGCS LSFR SEL |
| Gene ID: | 6799 |
| Uniprot: | P50226 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 34kDa |
| Observed MW: | 34kDa |
| Synonyms: | SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2 |
| Background: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described. |
| UniProt Protein Function: | SULT1A2: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. Belongs to the sulfotransferase 1 family. |
| UniProt Protein Details: | Protein type:EC 2.8.2.1; Energy Metabolism - sulfur; Transferase Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cytosol Molecular Function:aryl sulfotransferase activity; flavonol 3-sulfotransferase activity; protein binding; sulfotransferase activity Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine biosynthetic process; ethanol catabolic process; phenol metabolic process; sulfation; xenobiotic metabolic process |
| NCBI Summary: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P50226 |
| NCBI GenInfo Identifier: | 288558827 |
| NCBI Gene ID: | 6799 |
| NCBI Accession: | P50226.2 |
| UniProt Secondary Accession: | P50226,P78393, Q14CJ7, A9QY25, |
| UniProt Related Accession: | P50226 |
| Molecular Weight: | 34kDa |
| NCBI Full Name: | Sulfotransferase 1A2 |
| NCBI Synonym Full Names: | sulfotransferase family 1A member 2 |
| NCBI Official Symbol: | SULT1A2 |
| NCBI Official Synonym Symbols: | STP2; HAST4; P-PST; ST1A2; TSPST2 |
| NCBI Protein Information: | sulfotransferase 1A2 |
| UniProt Protein Name: | Sulfotransferase 1A2 |
| UniProt Synonym Protein Names: | Aryl sulfotransferase 2; Phenol sulfotransferase 2; Phenol-sulfating phenol sulfotransferase 2; P-PST 2 |
| Protein Family: | Sulfotransferase |
| UniProt Gene Name: | SULT1A2 |
 | Western blot analysis of extracts of various cell lines, using SULT1A2 antibody (CAB12851) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 3min. |
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