Anti-STK39 Antibody (CAB2275)
- SKU:
- CAB2275
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DCHT
- PASK
- SPAK
Description
| Product Name: | STK39 Rabbit mAb |
| Product Code: | CAB2275 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | DCHT, PASK, SPAK |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human STK39 |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, SH-SY5Y, Rat testis, Mouse testis |
| Immunogen: | A synthesized peptide derived from human STK39 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 27347 |
| Uniprot: | Q9UEW8 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 68kDa |
| Observed MW: | 71kDa |
| UniProt Protein Function: | STLK3: May act as a mediator of stress-activated signals. The phosphorylated form forms a complex with WNK2. Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
| UniProt Protein Details: | Protein type:Kinase, protein; EC 2.7.11.1; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; FRAY subfamily Chromosomal Location of Human Ortholog: 2q24.3 Cellular Component: apical plasma membrane; basolateral plasma membrane; cytoplasm; cytoskeleton; nucleus Molecular Function:ATP binding; protein binding; protein kinase binding; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity Biological Process: activation of protein kinase activity; negative regulation of protein amino acid phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of potassium ion transport; protein amino acid phosphorylation; regulation of apoptosis; regulation of blood pressure; regulation of inflammatory response; regulation of mitotic cell cycle; response to stress; stress-activated protein kinase signaling pathway |
| NCBI Summary: | This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UEW8 |
| NCBI GenInfo Identifier: | 317373508 |
| NCBI Gene ID: | 27347 |
| NCBI Accession: | Q9UEW8.3 |
| UniProt Secondary Accession: | Q9UEW8,O14774, Q53S90, Q53SL7, Q53SS1, Q9UER4, X5D9C8 |
| UniProt Related Accession: | Q9UEW8 |
| Molecular Weight: | 57,937 Da |
| NCBI Full Name: | STE20/SPS1-related proline-alanine-rich protein kinase |
| NCBI Synonym Full Names: | serine/threonine kinase 39 |
| NCBI Official Symbol: | STK39 |
| NCBI Official Synonym Symbols: | DCHT; PASK; SPAK |
| NCBI Protein Information: | STE20/SPS1-related proline-alanine-rich protein kinase |
| UniProt Protein Name: | STE20/SPS1-related proline-alanine-rich protein kinase |
| UniProt Synonym Protein Names: | DCHT; Serine/threonine-protein kinase 39 |
| Protein Family: | STE20/SPS1-related proline-alanine-rich protein kinase |
| UniProt Gene Name: | STK39 |
| UniProt Entry Name: | STK39_HUMAN |
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