Anti-STK38L Antibody (CAB15406)
- SKU:
- CAB15406
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-STK38L Antibody |
| Antibody SKU: | CAB15406 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-464 of human STK38L (NP_055815.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse small intestine, Mouse brain, Rat stomach, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-464 of human STK38L (NP_055815.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LIME FLPG GDMM TLLM KKDT LTEE ETQF YISE TVLA IDAI HQLG FIHR DIKP DNLL LDAK GHVK LSDF GLCT GLKK AHRT EFYR NLTH NPPS DFSF QNMN SKRK AETW KKNR RQLA YSTV GTPD YIAP EVFM QTGY NKLC DWWS LGVI MYEM LIGY PPFC SETP QETY RKVM NWKE TLVF PPEV PISE KAKD LILR FCID SENR IGNS GVEE IKGH PFFE GVDW EHIR ERPA AIPI EIKS IDDT SNFD DFPE SDIL QPVP NTTE PDYK SKDW VFLN YTYK RFEG LTQR GSIP TYMK AGKL |
| Gene ID: | 23012 |
| Uniprot: | Q9Y2H1 |
| Cellular Location: | Cytoplasm, Membrane, cytoskeleton |
| Calculated MW: | 43kDa/54kDa |
| Observed MW: | 54kDa |
| Synonyms: | STK38L, NDR2 |
| Background: |
| UniProt Protein Function: | NDR2: a non-receptor S/T kinase of the AGC group. Activated by binding of S100B which releases autoinhibitory N-lobe interactions, enabling ATP to bind followed by autophosphorylation of a serine in the kinase domain. A threonine in the C-terminal domain then undergoes calcium-dependent phosphorylation by an upstream kinase. Interactions between the phosphorylated threonine and the N-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of MOB1/MOBKL1A and MOB2/HCCA2 to the N-terminal of STK38L. May be involved in the regulation of structural processes in neuronal cells. |
| UniProt Protein Details: | Protein type:EC 2.7.11.1; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); AGC group; NDR family Chromosomal Location of Human Ortholog: 12p11.23 Cellular Component: actin cytoskeleton; cytoplasm Molecular Function:ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activity Biological Process: peptidyl-serine phosphorylation; protein amino acid phosphorylation; regulation of cellular component organization and biogenesis |
| UniProt Code: | Q9Y2H1 |
| NCBI GenInfo Identifier: | 56749668 |
| NCBI Gene ID: | 23012 |
| NCBI Accession: | Q9Y2H1.3 |
| UniProt Secondary Accession: | Q9Y2H1,Q8TBX7, A8K4U0, B4E3J8, |
| UniProt Related Accession: | Q9Y2H1 |
| Molecular Weight: | 43,170 Da |
| NCBI Full Name: | Serine/threonine-protein kinase 38-like |
| NCBI Synonym Full Names: | serine/threonine kinase 38 like |
| NCBI Official Symbol: | STK38L |
| NCBI Official Synonym Symbols: | NDR2 |
| NCBI Protein Information: | serine/threonine-protein kinase 38-like |
| UniProt Protein Name: | Serine/threonine-protein kinase 38-like |
| UniProt Synonym Protein Names: | NDR2 protein kinase; Nuclear Dbf2-related kinase 2 |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | STK38L |
| UniProt Entry Name: | ST38L_HUMAN |
 | Western blot analysis of extracts of various cell lines, using STK38L Rabbit pAb (CAB15406) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunofluorescence analysis of L929 cells using STK38L antibody (CAB15406) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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