Anti-SRSF4 Antibody (CAB6978)
- SKU:
- CAB6978
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-SRSF4 Antibody |
| Antibody SKU: | CAB6978 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPRV YIGR LSYQ ARER DVER FFKG YGKI LEVD LKNG YGFV EFDD LRDA DDAV YELN GKDL CGER VIVE HARG PRRD GSYG SGRS GYGY RRSG RDKY GPPT RTEY RLIV ENLS SRCS WQDL KDYM RQAG EVTY ADAH KGRK NEGV IEFV SYSD MKRA LEKL DGTE VNGR KIRL VEDK PGSR |
| Gene ID: | 6429 |
| Uniprot: | Q08170 |
| Cellular Location: | Nucleus speckle |
| Calculated MW: | 56kDa |
| Observed MW: | Refer to figures |
| Synonyms: | SRSF4, SFRS4, SRP75 |
| Background: | This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. |
| UniProt Protein Function: | SFRS4: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. |
| UniProt Protein Details: | Protein type:RNA splicing; RNA-binding; Spliceosome Chromosomal Location of Human Ortholog: 1p35.3 Cellular Component: nucleoplasm; nuclear speck; nucleus Molecular Function:nucleotide binding Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; hemopoietic progenitor cell differentiation; mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription |
| NCBI Summary: | This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009] |
| UniProt Code: | Q08170 |
| NCBI GenInfo Identifier: | 20981726 |
| NCBI Gene ID: | 6429 |
| NCBI Accession: | Q08170.2 |
| UniProt Secondary Accession: | Q08170,Q5VXP1, Q9BUA4, Q9UEB5, |
| UniProt Related Accession: | Q08170 |
| Molecular Weight: | |
| NCBI Full Name: | Serine/arginine-rich splicing factor 4 |
| NCBI Synonym Full Names: | serine/arginine-rich splicing factor 4 |
| NCBI Official Symbol: | SRSF4 |
| NCBI Official Synonym Symbols: | SFRS4; SRP75 |
| NCBI Protein Information: | serine/arginine-rich splicing factor 4; SRP001LB; SR splicing factor 4; pre-mRNA-splicing factor SRP75; splicing factor, arginine/serine-rich 4 |
| UniProt Protein Name: | Serine/arginine-rich splicing factor 4 |
| UniProt Synonym Protein Names: | Pre-mRNA-splicing factor SRP75; SRP001LB; Splicing factor, arginine/serine-rich 4 |
| Protein Family: | Serine/arginine-rich splicing factor |
| UniProt Gene Name: | SRSF4 |
| UniProt Entry Name: | SRSF4_HUMAN |
 | Immunofluorescence analysis of MCF-7 cells using SRSF4 antibody (CAB6978). Blue: DAPI for nuclear staining. |
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