Anti-SNAPC2 Antibody (CAB16069)
- SKU:
- CAB16069
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-SNAPC2 Antibody |
| Antibody SKU: | CAB16069 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-100 of human SNAPC2 (NP_003074.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-100 of human SNAPC2 (NP_003074.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GPAT WSAR EKRQ LVRL LQAR QGQP EPDA TELA RELR GRSE AEIR VFLQ QLKG RVAR EAIQ KVHP GGLQ GPRR REAQ PPAP I |
| Gene ID: | 6618 |
| Uniprot: | Q13487 |
| Cellular Location: | Nucleus |
| Calculated MW: | 35kDa |
| Observed MW: | Refer to figures |
| Synonyms: | SNAPC2, PTFDELTA, SNAP45 |
| Background: | This gene encodes a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | SNAPC2: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:transcription factor activity Biological Process: snRNA transcription; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter |
| NCBI Summary: | This gene encodes a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] |
| UniProt Code: | Q13487 |
| NCBI GenInfo Identifier: | 8134714 |
| NCBI Gene ID: | 6618 |
| NCBI Accession: | Q13487.1 |
| UniProt Secondary Accession: | Q13487,Q13486, B2RBZ6, D6W663, |
| UniProt Related Accession: | Q13487 |
| Molecular Weight: | 35,556 Da |
| NCBI Full Name: | snRNA-activating protein complex subunit 2 |
| NCBI Synonym Full Names: | small nuclear RNA activating complex polypeptide 2 |
| NCBI Official Symbol: | SNAPC2 |
| NCBI Official Synonym Symbols: | SNAP45; PTFDELTA |
| NCBI Protein Information: | snRNA-activating protein complex subunit 2 |
| UniProt Protein Name: | snRNA-activating protein complex subunit 2 |
| UniProt Synonym Protein Names: | Proximal sequence element-binding transcription factor subunit delta; PSE-binding factor subunit delta; PTF subunit delta; Small nuclear RNA-activating complex polypeptide 2; snRNA-activating protein complex 45 kDa subunit; SNAPc 45 kDa subunit |
| Protein Family: | snRNA-activating protein complex |
| UniProt Gene Name: | SNAPC2 |
| UniProt Entry Name: | SNPC2_HUMAN |
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