Anti-SLCO6A1 Antibody (CAB14963)

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SKU:
CAB14963
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Frequently bought together:

Description

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Antibody Name:Anti-SLCO6A1 Antibody
Antibody SKU:CAB14963
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 480-580 of human SLCO6A1 (NP_775759.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SH-SY5Y, 293T, A-549, NCI-H460, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 480-580 of human SLCO6A1 (NP_775759.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VQFA GINE DYDG TGKL GNLT APCN EKCR CSSS IYSS ICGR DDIE YFSP CFAG CTYS KAQN QKKM YYNC SCIK EGLI TADA EGDF IDAR PGKC DAKC YKLP L
Gene ID:133482
Uniprot:Q86UG4
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:51kDa/72kDa/79kDa
Observed MW:80kDa
Synonyms:SLCO6A1, CT48, GST, OATP-I, OATP6A1, OATPY
Background:
UniProt Protein Function:SLCO6A1: a multi-pass membrane protein strongly expressed in testis and weakly in spleen, brain, fetal brain and placenta. A member of the Cancer-Testis Antigen (CTA) superfamily. CTAs may play roles in embryonal development and tumor transformation or aspects of tumor progression. CTAs were once thought to be silenced in most normal adult tissues, with limited expression in fetal, placental, testis, and ovarian cells. These proteins are now known to be aberrantly expressed in various cancers and many are capable of eliciting humoral and cellular immune responses. Expressed in bladder, esophageal, brain and lung cancers. Spontaneous humoral immune responses have been detected in cancer patients. Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain. Note: This description may include information from RefSeq and UniProtKB
UniProt Protein Details:

Protein type:Cancer Testis Antigen (CTA); Membrane protein, integral; Transporter; Transporter, SLC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q21.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function:transporter activity

Biological Process: transport

UniProt Code:Q86UG4
NCBI GenInfo Identifier:160185610
NCBI Gene ID:133482
NCBI Accession:Q86UG4.2
UniProt Related Accession:Q86UG4
Molecular Weight:51kDa; 72kDa; 79kDa
NCBI Full Name:Solute carrier organic anion transporter family member 6A1
NCBI Synonym Full Names:solute carrier organic anion transporter family member 6A1
NCBI Official Symbol:SLCO6A1  
NCBI Official Synonym Symbols:GST; CT48; OATPY; OATP-I; OATP6A1  
NCBI Protein Information:solute carrier organic anion transporter family member 6A1
UniProt Protein Name:Solute carrier organic anion transporter family member 6A1
UniProt Synonym Protein Names:Cancer/testis antigen 48; CT48; Gonad-specific transporter; GST; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; OATP-I; Solute carrier family 21 member 19
Protein Family:Solute carrier organic anion transporter family
UniProt Gene Name:SLCO6A1  
UniProt Entry Name:SO6A1_HUMAN
Anti-SLCO6A1 Antibody (CAB14963)Western blot analysis of extracts of various cell lines, using SLCO6A1 Rabbit pAb (CAB14963) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.

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