Anti-SLC4A2 Antibody (CAB7729)
- SKU:
- CAB7729
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-SLC4A2 Antibody |
| Antibody SKU: | CAB7729 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human SLC4A2 (NP_001186623.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, A-549, Jurkat, HT-29 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human SLC4A2 (NP_001186623.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DDGG ASGR PLPK AQPG HRSY NLQE RRRI GSMT GAEQ ALLP RVPT DEIE AQTL ATAD LDLM KSHR FEDV PGVR RHLV RKNA KGST QSGR EGRE PGPT PRAR P |
| Gene ID: | 6522 |
| Uniprot: | P04920 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 135kDa/136kDa/137kDa |
| Observed MW: | 140kDa |
| Synonyms: | SLC4A2, AE2, BND3L, EPB3L1, HKB3, NBND3 |
| Background: | This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers. |
| UniProt Protein Function: | Plasma membrane anion exchange protein of wide distribution. |
| NCBI Summary: | This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers. [provided by RefSeq, Nov 2016] |
| UniProt Code: | P04920 |
| NCBI GenInfo Identifier: | 314122220 |
| NCBI Gene ID: | 6522 |
| NCBI Accession: | NP_001186621.1 |
| UniProt Secondary Accession: | P04920,Q45EY5, Q969L3, B2R6T0, B4DIT0, D3DX05, F8W682 |
| UniProt Related Accession: | P04920 |
| Molecular Weight: | 136,247 Da |
| NCBI Full Name: | anion exchange protein 2 isoform 1 |
| NCBI Synonym Full Names: | solute carrier family 4 member 2 |
| NCBI Official Symbol: | SLC4A2 |
| NCBI Official Synonym Symbols: | AE2; HKB3; BND3L; NBND3; EPB3L1 |
| NCBI Protein Information: | anion exchange protein 2 |
| UniProt Protein Name: | Anion exchange protein 2 |
| UniProt Synonym Protein Names: | Non-erythroid band 3-like protein; BND3L; Solute carrier family 4 member 2 |
| UniProt Gene Name: | SLC4A2 |
 | Western blot analysis of extracts of various cell lines, using SLC4A2 antibody (CAB7729) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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