Anti-SLC34A2 Antibody (CAB9460)
- SKU:
- CAB9460
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-SLC34A2 Antibody |
| Antibody SKU: | CAB9460 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-362 of human SLC34A2 (NP_001171469.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, 293T, HT-29, MCF7, Mouse small intestine, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-362 of human SLC34A2 (NP_001171469.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EVAT HYLE IITQ LIVE SFHF KNGE DAPD LLKV ITKP FTKL IVQL DKKV ISQI AMND EKAK NKSL VKIW CKTF TNKT QINV TVPS TANC TSPS LCWT DGIQ NWTM KNVT YKEN IAKC QHIF VNFH LPDL A |
| Gene ID: | 10568 |
| Uniprot: | O95436 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 75kDa |
| Observed MW: | 76kDa |
| Synonyms: | SLC34A2, NAPI-3B, NAPI-IIb, NPTIIb |
| Background: | The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene. |
| UniProt Protein Function: | May be involved in actively transporting phosphate into cells via Na+ cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli. |
| NCBI Summary: | The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2010] |
| UniProt Code: | O95436 |
| NCBI GenInfo Identifier: | 295789158 |
| NCBI Gene ID: | 10568 |
| NCBI Accession: | NP_001171469.1 |
| UniProt Secondary Accession: | O95436,Q8N2K2, Q8WYA9, Q9P0V7, A5PL17, |
| UniProt Related Accession: | O95436 |
| Molecular Weight: | 75,657 Da |
| NCBI Full Name: | sodium-dependent phosphate transport protein 2B isoform b |
| NCBI Synonym Full Names: | solute carrier family 34 member 2 |
| NCBI Official Symbol: | SLC34A2 |
| NCBI Official Synonym Symbols: | NPTIIb; NAPI-3B; NAPI-IIb |
| NCBI Protein Information: | sodium-dependent phosphate transport protein 2B |
| UniProt Protein Name: | Sodium-dependent phosphate transport protein 2B |
| UniProt Synonym Protein Names: | Na(+)-dependent phosphate cotransporter 2B; NaPi3b; Sodium/phosphate cotransporter 2B; Na(+)/Pi cotransporter 2B; NaPi-2b; Solute carrier family 34 member 2 |
| UniProt Gene Name: | SLC34A2 |
 | Western blot analysis of extracts of various cell lines, using SLC34A2 antibody (CAB9460) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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