Anti-SLC32A1 Antibody (CAB12610)

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SKU:
CAB12610
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
Frequently bought together:

Description

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Antibody Name:Anti-SLC32A1 Antibody
Antibody SKU:CAB12610
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SLC32A1 (NP_542119.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, U-251MG, Mouse brain, Mouse pancreas, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SLC32A1 (NP_542119.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATL LRSK LSNV ATSV SNKS QAKM SGMF ARMG FQAA TDEE AVGF AHCD DLDF EHRQ GLQM DILK AEGE PCGD EGAE APVE GDIH YQRG SGAP LPPS GSKD QVGG GGEF GGHD KPKI TAWE
Gene ID:140679
Uniprot:Q9H598
Cellular Location:Cytoplasmic vesicle membrane, Multi-pass membrane protein
Calculated MW:57kDa
Observed MW:68kDa
Synonyms:SLC32A1, VGAT, VIAAT
Background:The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.
UniProt Protein Function:SLC32A1: Involved in the uptake of GABA and glycine into the synaptic vesicles. Belongs to the amino acid/polyamine transporter 2 family.
UniProt Protein Details:

Protein type:Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: neuron projection; synaptic vesicle membrane; dendrite; plasma membrane; integral to membrane

Molecular Function:glycine transmembrane transporter activity; gamma-aminobutyric acid:hydrogen symporter activity; amino acid transmembrane transporter activity

Biological Process: glycine transport; synaptic transmission; neurotransmitter secretion; ion transport; transmembrane transport; aging; gamma-aminobutyric acid transport

NCBI Summary:The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II. [provided by RefSeq, Jul 2008]
UniProt Code:Q9H598
NCBI GenInfo Identifier:29428257
NCBI Gene ID:140679
NCBI Accession:Q9H598.2
UniProt Secondary Accession:Q9H598,Q8N489,
UniProt Related Accession:Q9H598
Molecular Weight:525
NCBI Full Name:Vesicular inhibitory amino acid transporter
NCBI Synonym Full Names:solute carrier family 32 (GABA vesicular transporter), member 1
NCBI Official Symbol:SLC32A1  
NCBI Official Synonym Symbols:VGAT; VIAAT  
NCBI Protein Information:vesicular inhibitory amino acid transporter; hVIAAT; vesicular GABA transporter; GABA and glycine transporter; solute carrier family 32 member 1
UniProt Protein Name:Vesicular inhibitory amino acid transporter
UniProt Synonym Protein Names:GABA and glycine transporter; Solute carrier family 32 member 1; Vesicular GABA transporter; hVIAAT
Protein Family:Vesicular GABA transporter
UniProt Gene Name:SLC32A1  
UniProt Entry Name:VIAAT_HUMAN
Anti-SLC32A1 Antibody (CAB12610)Western blot analysis of extracts of various cell lines, using SLC32A1 antibody (CAB12610) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

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