Anti-SLC26A11 Antibody (CAB17276)
- SKU:
- CAB17276
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-SLC26A11 Antibody |
| Antibody SKU: | CAB17276 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SLC26A11 (NP_001159819.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SLC26A11 (NP_001159819.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EILS RALE VSPP RCLV LECT HVCS IDYT VVLG LGEL LQDF QKQG VALA FVGL QVPV LRVL LSAD LKGF QYFS TLEE AEKH LRQE PGTQ PYNI REDS ILDQ K |
| Gene ID: | 284129 |
| Uniprot: | Q86WA9 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | SLC26A11 |
| Background: | This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger inhibitor 4, 4'-diisothiocyanostilbene-2, 2'-disulfonic acid. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | SLC26A11: Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: endoplasmic reticulum; Golgi apparatus; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; lysosomal membrane; nucleoplasm; plasma membrane Molecular Function:anion transmembrane transporter activity; anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; oxalate transmembrane transporter activity; sulfate transmembrane transporter activity Biological Process: bicarbonate transport; regulation of intracellular pH; regulation of membrane potential; sulfate transport |
| NCBI Summary: | This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] |
| UniProt Code: | Q86WA9 |
| NCBI GenInfo Identifier: | 23273535 |
| NCBI Gene ID: | 284129 |
| NCBI Accession: | BC035900 |
| UniProt Secondary Accession: | Q86WA9,Q86VX1, Q86YX7, Q8IV11, Q8N2I1, Q8NG03, B2RCI7 |
| UniProt Related Accession: | Q86WA9 |
| Molecular Weight: | 65,299 Da |
| NCBI Full Name: | Homo sapiens solute carrier family 26, member 11, mRNA |
| NCBI Synonym Full Names: | solute carrier family 26 member 11 |
| NCBI Official Symbol: | SLC26A11 |
| NCBI Protein Information: | sodium-independent sulfate anion transporter |
| UniProt Protein Name: | Sodium-independent sulfate anion transporter |
| UniProt Synonym Protein Names: | Solute carrier family 26 member 11 |
| Protein Family: | Sodium-independent sulfate anion transporter |
| UniProt Gene Name: | SLC26A11 |
| UniProt Entry Name: | S2611_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC26A11 antibody (CAB17276) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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