Anti-SLC25A39 Antibody (CAB15450)
- SKU:
- CAB15450
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-SLC25A39 Antibody |
| Antibody SKU: | CAB15450 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-250 of human SLC25A39 (NP_057100.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Mouse spleen, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-250 of human SLC25A39 (NP_057100.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VISP LELM RTKL QAQH VSYR ELGA CVRT AVAQ GGWR SLWL GWGP TALR DVPF SALY WFNY ELVK SWLN GFRP KDQT SVGM S |
| Gene ID: | 51629 |
| Uniprot: | Q9BZJ4 |
| Cellular Location: | Mitochondrion inner membrane, Multi-pass membrane protein |
| Calculated MW: | 38kDa/39kDa |
| Observed MW: | 39kDa |
| Synonyms: | SLC25A39, CGI-69, CGI69 |
| Background: | This gene encodes a member of the SLC25 transporter or mitochondrial carrier family of proteins. Members of this family are encoded by the nuclear genome while their protein products are usually embedded in the inner mitochondrial membrane and exhibit wide-ranging substrate specificity. Although the encoded protein is currently considered an orphan transporter, this protein is related to other carriers known to transport amino acids. This protein may play a role in iron homeostasis. |
| UniProt Protein Function: | SLC25A39: Required for normal heme biosynthesis. Belongs to the mitochondrial carrier family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter, SLC family; Mitochondrial; Membrane protein, multi-pass; Transporter Chromosomal Location of Human Ortholog: 17q12 Cellular Component: mitochondrial inner membrane; integral to membrane Biological Process: transport; heme biosynthetic process |
| NCBI Summary: | SLC25A39 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9BZJ4 |
| NCBI GenInfo Identifier: | 66911248 |
| NCBI Gene ID: | 51629 |
| NCBI Accession: | AAH96819.1 |
| UniProt Secondary Accession: | Q9BZJ4,Q4V9M1, Q9P182, Q9UF66, Q9Y379, A8JZZ2, D3DX51 D3DX54, |
| UniProt Related Accession: | Q9BZJ4 |
| Molecular Weight: | 39 kDa (MW of target protein) |
| NCBI Full Name: | SLC25A39 protein |
| NCBI Synonym Full Names: | solute carrier family 25, member 39 |
| NCBI Official Symbol: | SLC25A39 |
| NCBI Official Synonym Symbols: | CGI69; CGI-69 |
| NCBI Protein Information: | solute carrier family 25 member 39 |
| UniProt Protein Name: | Solute carrier family 25 member 39 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC25A39 |
| UniProt Entry Name: | S2539_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC25A39 antibody (CAB15450) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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