Anti-SLC25A17 Antibody (CAB14840)
- SKU:
- CAB14840
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-SLC25A17 Antibody |
| Antibody SKU: | CAB14840 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC25A17 (NP_006349.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse liver, Mouse kidney |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC25A17 (NP_006349.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IDAF HQII RDEG ISAL WNGT FPSL LLVF NPAI QFMF YEGL KRQL LKKR MKLS SLDV FIIG AVAK AIAT TVTY PLQT VQSI LRFG RHRL NPEN RTLG SLRN I |
| Gene ID: | 10478 |
| Uniprot: | O43808 |
| Cellular Location: | Cytoplasm, Multi-pass membrane protein, Peroxisome membrane |
| Calculated MW: | 34kDa |
| Observed MW: | 34kDa |
| Synonyms: | SLC25A17, PMP34 |
| Background: | This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | SLC25A17: Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro. Belongs to the mitochondrial carrier family. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: integral to peroxisomal membrane; intracellular membrane-bound organelle; membrane; peroxisomal membrane; peroxisome Molecular Function:adenine nucleotide transmembrane transporter activity; ADP transmembrane transporter activity; ATP transmembrane transporter activity; chaperone binding; coenzyme A transmembrane transporter activity; FAD transmembrane transporter activity; NAD transporter activity; protein binding; structural constituent of ribosome Biological Process: ATP transport; fatty acid alpha-oxidation; fatty acid beta-oxidation; fatty acid transport; translation |
| NCBI Summary: | This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | O43808 |
| NCBI GenInfo Identifier: | 12643354 |
| NCBI Gene ID: | 10478 |
| NCBI Accession: | O43808.1 |
| UniProt Secondary Accession: | O43808,Q5TFL0, Q9UGW8, Q9UGY7, A8KA59, |
| UniProt Related Accession: | O43808 |
| Molecular Weight: | 34,567 Da |
| NCBI Full Name: | Peroxisomal membrane protein PMP34 |
| NCBI Synonym Full Names: | solute carrier family 25 member 17 |
| NCBI Official Symbol: | SLC25A17 |
| NCBI Official Synonym Symbols: | PMP34 |
| NCBI Protein Information: | peroxisomal membrane protein PMP34 |
| UniProt Protein Name: | Peroxisomal membrane protein PMP34 |
| UniProt Synonym Protein Names: | 34 kDa peroxisomal membrane protein; Solute carrier family 25 member 17 |
| Protein Family: | Peroxisomal membrane protein |
| UniProt Gene Name: | SLC25A17 |
| UniProt Entry Name: | PM34_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC25A17 Rabbit pAb (CAB14840) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of 293T cells using SLC25A17 antibody (CAB14840) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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