Anti-SLC24A5 Antibody (CAB15223)
- SKU:
- CAB15223
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-SLC24A5 Antibody |
| Antibody SKU: | CAB15223 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human SLC24A5 (NP_995322.1). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human SLC24A5 (NP_995322.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | INQY IIKK CSPC CACL AKAM ERSE QQPL MGWE DEGQ PFIR RQSR TDSG IFYE DSGY SQLS ISLH GLSQ VSED PPSV FNMP E |
| Gene ID: | 283652 |
| Uniprot: | Q71RS6 |
| Cellular Location: | Golgi apparatus, Melanosome, Multi-pass membrane protein, trans-Golgi network membrane |
| Calculated MW: | 48kDa/54kDa |
| Observed MW: |
| Synonyms: | SLC24A5, JSX, NCKX5, OCA6, SHEP4 |
| Background: | This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. |
| UniProt Protein Function: | Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-Calcium exchanger in melanocytes. Probably transports 1 Ca2+ and 1 K+ to the melanosome in exchange for 4 cytoplasmic Na+. |
| NCBI Summary: | This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q71RS6 |
| NCBI GenInfo Identifier: | 45504369 |
| NCBI Gene ID: | 283652 |
| NCBI Accession: | NP_995322.1 |
| UniProt Secondary Accession: | Q71RS6,Q14CT4, Q6DKH3, A5X8Z8, A5X8Z9, |
| UniProt Related Accession: | Q71RS6 |
| Molecular Weight: | 48,016 Da |
| NCBI Full Name: | sodium/potassium/calcium exchanger 5 |
| NCBI Synonym Full Names: | solute carrier family 24 member 5 |
| NCBI Official Symbol: | SLC24A5 |
| NCBI Official Synonym Symbols: | JSX; OCA6; NCKX5; SHEP4 |
| NCBI Protein Information: | sodium/potassium/calcium exchanger 5 |
| UniProt Protein Name: | Sodium/potassium/calcium exchanger 5 |
| UniProt Synonym Protein Names: | Na(+)/K(+)/Ca(2+)-exchange protein 5; Solute carrier family 24 member 5 |
| Protein Family: | Sodium/potassium/calcium exchanger |
| UniProt Gene Name: | SLC24A5 |
 | Immunofluorescence analysis of Hela cells using SLC24A5 antibody (CAB15223) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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