Anti-SIGLEC6 Antibody (CAB12387)

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SKU:
CAB12387
Product type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-SIGLEC6 Antibody
Antibody SKU:CAB12387
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 27-220 of human SIGLEC6 (NP_942142.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 27-220 of human SIGLEC6 (NP_942142.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QERR FQLE GPES LTVQ EGLC VLVP CRLP TTLP ASYY GYGY WFLE GADV PVAT NDPD EEVQ EETR GRFH LLWD PRRK NCSL SIRD ARRR DNAA YFFR LKSK WMKY GYTS SKLS VRVM ALTH RPNI SIPG TLES GHPS NLTC SVPW VCEQ GTPP IFSW MSAA PTSL GPRT TQSS VLTI TPRP QDHS TNLT CQVT FP
Gene ID:946
Uniprot:O43699
Cellular Location:Cell membrane, Secreted, Single-pass type I membrane protein
Calculated MW:37kDa/38kDa/42kDa/44kDa/48kDa/49kDa
Observed MW:50kDa
Synonyms:SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1
Background:
UniProt Protein Function:Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
NCBI Summary:This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016]
UniProt Code:O43699
NCBI GenInfo Identifier:215273884
NCBI Gene ID:946
NCBI Accession:O43699.2
UniProt Secondary Accession:O43699,O15388, O43700, A8MV71, B2RTS8, C9JBE5, F8WA78
UniProt Related Accession:O43699
Molecular Weight:44,348 Da
NCBI Full Name:Sialic acid-binding Ig-like lectin 6
NCBI Synonym Full Names:sialic acid binding Ig like lectin 6
NCBI Official Symbol:SIGLEC6  
NCBI Official Synonym Symbols:CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327  
NCBI Protein Information:sialic acid-binding Ig-like lectin 6
UniProt Protein Name:Sialic acid-binding Ig-like lectin 6
UniProt Synonym Protein Names:CD33 antigen-like 1; CDw327; Obesity-binding protein 1; OB-BP1; CD_antigen: CD327
Protein Family:Sialic acid-binding Ig-like lectin
UniProt Gene Name:SIGLEC6  
Anti-SIGLEC6 Antibody (CAB12387)Western blot analysis of extracts of mouse kidney, using SIGLEC6 antibody (CAB12387) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

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