Anti-SERPINB13 Antibody (CAB13744)
- SKU:
- CAB13744
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-SERPINB13 Antibody |
| Antibody SKU: | CAB13744 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SERPINB13 (NP_036529.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse uterus, Rat uterus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SERPINB13 (NP_036529.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDSL GAVS TRLG FDLF KELK KTND GNIF FSPV GILT AIGM VLLG TRGA TASQ LEEV FHSE KETK SSRI KAEE KEVI ENTE AVHQ QFQK FLTE ISKL TNDY ELNI TNRL FGEK TYLF LQKY LDYV EKYY HASL EPVD FVNA |
| Gene ID: | 5275 |
| Uniprot: | Q9UIV8 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 38kDa/44kDa |
| Observed MW: | 44kDa |
| Synonyms: | SERPINB13, HSHUR7SEQ, HUR7, PI13, headpin |
| Background: | The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein inhibits the activity of cathepsin K and is itself transcriptionally repressed by RUNX1. This gene is downregulated in many types of cancer. |
| UniProt Protein Function: | SERPINB13: May play a role in the proliferation or differentiation of keratinocytes. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.33 Cellular Component: nucleoplasm; extracellular space; cytoplasm; nucleolus Molecular Function:serine-type endopeptidase inhibitor activity; protease binding; cysteine protease inhibitor activity Biological Process: regulation of proteolysis; response to UV |
| UniProt Code: | Q9UIV8 |
| NCBI GenInfo Identifier: | 8393956 |
| NCBI Gene ID: | 5275 |
| NCBI Accession: | NP_036529.1 |
| UniProt Secondary Accession: | Q9UIV8,Q3MII2, Q9HCX1, Q9UBW1, Q9UKG0, A8K2Q8, |
| UniProt Related Accession: | Q9UIV8 |
| Molecular Weight: | 44,276 Da |
| NCBI Full Name: | serpin B13 |
| NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| NCBI Official Symbol: | SERPINB13 |
| NCBI Official Synonym Symbols: | HUR7; PI13; headpin; HSHUR7SEQ |
| NCBI Protein Information: | serpin B13; PI-13; HURPIN; peptidase inhibitor 13; proteinase inhibitor 13; haCaT UV-repressible serpin; UV-B repressed sequence, HUR 7; protease inhibitor 13 (hurpin, headpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 |
| UniProt Protein Name: | Serpin B13 |
| UniProt Synonym Protein Names: | HaCaT UV-repressible serpin; Hurpin; Headpin; Peptidase inhibitor 13; PI-13; Proteinase inhibitor 13 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB13 |
| UniProt Entry Name: | SPB13_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SERPINB13 antibody (CAB13744) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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