Anti-SERPINA10 Antibody (CAB7106)
- SKU:
- CAB7106
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
| Antibody Name: | Anti-SERPINA10 Antibody |
| Antibody SKU: | CAB7106 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Mouse liver, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FAFI HKDF DVKE TFFN LSKR YFDT ECVP MNFR NASQ AKRL MNHY INKE TRGK IPKL FDEI NPET KLIL VDYI LFKG KWLT PFDP VFTE VDTF HLDK YKTI KVPM MYGA GKFA STFD KNFR CHVL KLPY QGNA TMLV VLME KMGD HLAL EDYL TTDL VETW LRNM KTRN MEVF FPKF KLDQ KYEM HELL RQMG IRRI FSPF ADLS ELSA TGRN LQVS RVLQ RTVI EVDE RGTE AVAG ILSE ITAY SMPP VIKV DRPF HFMI YEET SGML LFLG RVVN PTLL |
| Gene ID: | 51156 |
| Uniprot: | Q9UK55 |
| Cellular Location: | Secreted |
| Calculated MW: | 50kDa |
| Observed MW: | 51kDa |
| Synonyms: | SERPINA10, PZI, ZPI |
| Background: | The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | SERPINA10: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Belongs to the serpin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 14q32.13 Cellular Component: extracellular space Molecular Function:serine-type endopeptidase inhibitor activity; heparin binding Biological Process: regulation of acrosome reaction; blood coagulation |
| NCBI Summary: | The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010] |
| UniProt Code: | Q9UK55 |
| NCBI GenInfo Identifier: | 12585541 |
| NCBI Gene ID: | 51156 |
| NCBI Accession: | Q9UK55.1 |
| UniProt Secondary Accession: | Q9UK55,Q6UWX9, Q86U20, A5Z2A5, |
| UniProt Related Accession: | Q9UK55 |
| Molecular Weight: | 444 |
| NCBI Full Name: | Protein Z-dependent protease inhibitor |
| NCBI Synonym Full Names: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| NCBI Official Symbol: | SERPINA10 |
| NCBI Official Synonym Symbols: | PZI; ZPI |
| NCBI Protein Information: | protein Z-dependent protease inhibitor; serpin A10; PZ-dependent protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| UniProt Protein Name: | Protein Z-dependent protease inhibitor |
| UniProt Synonym Protein Names: | Serpin A10 |
| Protein Family: | Protein Z-dependent protease inhibitor |
| UniProt Gene Name: | SERPINA10 |
| UniProt Entry Name: | ZPI_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SERPINA10 antibody (CAB7106) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s. |
 | Immunohistochemistry of paraffin-embedded mouse lung using SERPINA10 antibody (CAB7106) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using SERPINA10 antibody (CAB7106) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of PC-12 cells using SERPINA10 antibody (CAB7106) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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