Anti-SEC13 Antibody (CAB11613)
- SKU:
- CAB11613
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-SEC13 Antibody |
| Antibody SKU: | CAB11613 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of human SEC13 (NP_899195.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, HeLa, 293T, HT-29, Mouse kidney, Mouse liver, Rat ovary |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of human SEC13 (NP_899195.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVSV INTV DTSH EDMI HDAQ MDYY GTRL ATCS SDRS VKIF DVRN GGQI LIAD LRGH EGPV WQVA WAHP MYGN ILAS CSYD RKVI IWRE ENGT WEKS HEHA GHDS SVNS VCWA PHDY GLIL ACGS SDGA ISLL TYTG EGQW EVKK INNA HTIG CNAV SWAP AVVP GSLI DHPS GQKP NYIK RFAS GGCD NLIK LWKE EEDG QWKE EQKL EAHS DWVR DVAW APSI GLPT STIA SCSQ DGRV FIWT CDDA SSNT WSPK LLHK FNDV VWHV SWSI TANI LAVS GGDN KVTL WKES VDGQ WVCI SDVN KGQG SVSA SVTE GQQN EQ |
| Gene ID: | 6396 |
| Uniprot: | P55735 |
| Cellular Location: | COPII-coated vesicle membrane, Cytoplasmic side, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, nuclear pore complex |
| Calculated MW: | 34kDa/35kDa/40kDa |
| Observed MW: | 38kDa |
| Synonyms: | SEC13, D3S1231E, SEC13L1, SEC13R, npp-20 |
| Background: | The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. |
| UniProt Protein Function: | SEC13: Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Belongs to the WD repeat SEC13 family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p25-p24 Cellular Component: cytosol; endoplasmic reticulum membrane; intracellular membrane-bound organelle; kinetochore; nuclear envelope; nucleoplasm Molecular Function:protein binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; positive regulation of TOR signaling pathway; sister chromatid cohesion |
| NCBI Summary: | The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2008] |
| UniProt Code: | P55735 |
| NCBI GenInfo Identifier: | 50403748 |
| NCBI Gene ID: | 6396 |
| NCBI Accession: | P55735.3 |
| UniProt Secondary Accession: | P55735,Q5BJF0, Q9BRM6, Q9BUG7, A8MV37, B4DXJ1, |
| UniProt Related Accession: | P55735 |
| Molecular Weight: | 40,747 Da |
| NCBI Full Name: | Protein SEC13 homolog |
| NCBI Synonym Full Names: | SEC13 homolog, nuclear pore and COPII coat complex component |
| NCBI Official Symbol: | SEC13 |
| NCBI Official Synonym Symbols: | SEC13R; npp-20; SEC13L1; D3S1231E |
| NCBI Protein Information: | protein SEC13 homolog |
| UniProt Protein Name: | Protein SEC13 homolog |
| UniProt Synonym Protein Names: | SEC13-like protein 1; SEC13-related protein |
| Protein Family: | Protein transport protein |
| UniProt Gene Name: | SEC13 |
| UniProt Entry Name: | SEC13_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SEC13 antibody (CAB11613) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
Anti-SLC20A2 Antibody (CAB6739)
