Anti-SAM68 Antibody (CAB3886)
- SKU:
- CAB3886
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-SAM68 Antibody |
| Antibody SKU: | CAB3886 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SAM68 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, NIH/3T3, Jurkat, Rat testis |
| Immunogen: | A synthesized peptide derived from human SAM68 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10657 |
| Uniprot: | Q07666 |
| Cellular Location: | |
| Calculated MW: | 68 kDa |
| Observed MW: | 68KDa |
| Synonyms: | Sam68, p62, p68 |
| Background: | This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
| UniProt Protein Function: | KHDRBS1: a nuclear RNA-binding protein. May be involved in slicing and mRNA transport. Associates with src in mitosis. Binds to RNA via a heteronuclear ribonucleoprotein K homology domain. Exerts functionally separable effects on cell proliferation and survival, dependent on its ability to bind specifically to RNA. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 1p32 Cellular Component: nucleoplasm; membrane; cytoplasm; nucleus Molecular Function:identical protein binding; protein binding; SH3/SH2 adaptor activity; DNA binding; RNA binding; protein complex binding; poly(U) binding; SH3 domain binding; poly(A) binding Biological Process: transcription, DNA-dependent; positive regulation of signal transduction; positive regulation of RNA export from nucleus; regulation of protein stability; signal transduction; positive regulation of translational initiation; cell proliferation; cell surface receptor linked signal transduction; regulation of RNA export from nucleus; mRNA processing; cell cycle arrest; G2/M transition of mitotic cell cycle; negative regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q07666 |
| NCBI GenInfo Identifier: | 62511098 |
| NCBI Gene ID: | 10657 |
| NCBI Accession: | Q07666.1 |
| UniProt Related Accession: | Q07666 |
| Molecular Weight: | ~ 48kDa |
| NCBI Full Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
| NCBI Synonym Full Names: | KH RNA binding domain containing, signal transduction associated 1 |
| NCBI Official Symbol: | KHDRBS1 |
| NCBI Official Synonym Symbols: | p62; p68; Sam68 |
| NCBI Protein Information: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
| UniProt Protein Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
| UniProt Synonym Protein Names: | GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68 |
| UniProt Gene Name: | KHDRBS1 |
| UniProt Entry Name: | KHDR1_HUMAN |
 | Western blot - SAM68 Rabbit mAb (CAB3886) |
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