Anti-S100A10 Antibody (CAB1987)

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SKU:
CAB1987
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Monkey
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-S100A10 Antibody
Antibody SKU:CAB1987
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat, Monkey
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A10 (NP_002957.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat, Monkey
Positive Samples:HT-29, VERO, HeLa, A-549, NIH/3T3, RAW264.7, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A10 (NP_002957.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPSQ MEHA METM MFTF HKFA GDKG YLTK EDLR VLME KEFP GFLE NQKD PLAV DKIM KDLD QCRD GKVG FQSF FSLI AGLT IACN DYFV VHMK QKGK K
Gene ID:6281
Uniprot:P60903
Cellular Location:
Calculated MW:11kDa
Observed MW:11kDa
Anti-S100A10 Antibody (CAB1987)Western blot - S100A10 Rabbit pAb (CAB1987)
Synonyms:S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10
Background:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.
UniProt Protein Function:S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family.
UniProt Protein Details:

Protein type:Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extrinsic to plasma membrane; lipid raft

Molecular Function:protein binding; protein homodimerization activity; calcium ion binding; lipid binding

Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding

NCBI Summary:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
UniProt Code:P60903
NCBI GenInfo Identifier:46397706
NCBI Gene ID:6281
NCBI Accession:P60903.2
UniProt Related Accession:P60903
Molecular Weight:11kDa
NCBI Full Name:Protein S100-A10
NCBI Synonym Full Names:S100 calcium binding protein A10
NCBI Official Symbol:S100A10  
NCBI Official Synonym Symbols:42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG  
NCBI Protein Information:protein S100-A10
UniProt Protein Name:Protein S100-A10
UniProt Synonym Protein Names:Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Protein Family:Protein
UniProt Gene Name:S100A10  
UniProt Entry Name:S10AA_HUMAN

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