Anti-RTN1 Antibody (CAB16427)
- SKU:
- CAB16427
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-RTN1 Antibody |
| Antibody SKU: | CAB16427 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human RTN1 (NP_066959.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human RTN1 (NP_066959.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TGVA GVSS AMDH TFST TSKD GEGS CYTS LISD ICYP PQED STYF TGIL QKEN GHVT ISES PEEL GTPG PSLP DVPG IESR GLFS SDSG IEMT PAES TEVN KILA DPLD QMKA EAYK YIDI TRPE EVKH QEQH HPEL EDKD LDFK NKDT DISI KPEG VREP DKPA PVEG KIIK DHLL EEST FAPY IDDL SEEQ RRAP QITT PVKI TLTE IEPS VETT TQEK TPEK QDIC LKPS PDTV PTVT VSEP EDDS PGSI TPPS SGTE P |
| Gene ID: | 6252 |
| Uniprot: | Q16799 |
| Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Calculated MW: | 23kDa/38kDa/83kDa |
| Observed MW: | 24kDa |
| Synonyms: | RTN1, NSP |
| Background: | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | RTN1: May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral; Cell development/differentiation Chromosomal Location of Human Ortholog: 14q23.1 Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane Molecular Function:protein binding Biological Process: neuron differentiation |
| NCBI Summary: | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011] |
| UniProt Code: | Q16799 |
| NCBI GenInfo Identifier: | 12643733 |
| NCBI Gene ID: | 6252 |
| NCBI Accession: | Q16799.1 |
| UniProt Related Accession: | Q16799 |
| Molecular Weight: | 84 kDa |
| NCBI Full Name: | Reticulon-1 |
| NCBI Synonym Full Names: | reticulon 1 |
| NCBI Official Symbol: | RTN1 |
| NCBI Official Synonym Symbols: | NSP |
| NCBI Protein Information: | reticulon-1 |
| UniProt Protein Name: | Reticulon-1 |
| UniProt Synonym Protein Names: | Neuroendocrine-specific protein |
| Protein Family: | Reticulon |
| UniProt Gene Name: | RTN1 |
| UniProt Entry Name: | RTN1_HUMAN |
 | Western blot analysis of extracts of mouse lung, using RTN1 antibody (CAB16427) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 5 min. |
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