| Background: | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene. |
| UniProt Protein Function: | RPL36A: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene. [provided by RefSeq, Jan 2011] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: Xq22.1 Cellular Component: cytosol Molecular Function:protein binding; structural constituent of ribosome Biological Process: mRNA catabolic process, nonsense-mediated decay; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translational initiation; viral transcription |
| NCBI Summary: | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene. [provided by RefSeq, Jan 2011] |
| UniProt Code: | P83881 |
| NCBI GenInfo Identifier: | 47117731 |
| NCBI Gene ID: | 6173 |
| NCBI Accession: | P83881.2 |
| UniProt Secondary Accession: | P83881,P09896, P10661, Q08ES5, Q5J9I6, |
| UniProt Related Accession: | P83881 |
| Molecular Weight: | 12,441 Da |
| NCBI Full Name: | 60S ribosomal protein L36a |
| NCBI Synonym Full Names: | ribosomal protein L36a |
| NCBI Official Symbol: | RPL36A |
| NCBI Official Synonym Symbols: | L36A; L44L; MIG6; RPL44 |
| NCBI Protein Information: | 60S ribosomal protein L36a |
| UniProt Protein Name: | 60S ribosomal protein L36a |
| UniProt Synonym Protein Names: | 60S ribosomal protein L44; Cell growth-inhibiting gene 15 protein; Cell migration-inducing gene 6 protein |
| Protein Family: | 60S ribosomal protein |
| UniProt Gene Name: | RPL36A |
| UniProt Entry Name: | RL36A_HUMAN |
