Anti-RND1 Antibody (CAB13705)
- SKU:
- CAB13705
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-RND1 Antibody |
| Antibody SKU: | CAB13705 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 103-232 of human RND1 (NP_055285.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Mouse liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 103-232 of human RND1 (NP_055285.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ALKK WRTE ILDY CPST RVLL IGCK TDLR TDLS TLME LSHQ KQAP ISYE QGCA IAKQ LGAE IYLE GSAF TSEK SIHS IFRT ASML CLNK PSPL PQKS PVRS LSKR LLHL PSRS ELIS STFK KEKA KSCS IM |
| Gene ID: | 27289 |
| Uniprot: | Q92730 |
| Cellular Location: | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, cytoskeleton |
| Calculated MW: | 26kDa |
| Observed MW: | 26kDa |
| Synonyms: | RND1, ARHS, RHO6, RHOS |
| Background: | This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. |
| UniProt Protein Function: | Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. |
| NCBI Summary: | This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014] |
| UniProt Code: | Q92730 |
| NCBI GenInfo Identifier: | 7657514 |
| NCBI Gene ID: | 27289 |
| NCBI Accession: | NP_055285.1 |
| UniProt Secondary Accession: | Q92730,A8K9P7, |
| UniProt Related Accession: | Q92730 |
| Molecular Weight: | Calculated: 26kDaObserved: 26kDa |
| NCBI Full Name: | rho-related GTP-binding protein Rho6 |
| NCBI Synonym Full Names: | Rho family GTPase 1 |
| NCBI Official Symbol: | RND1 |
| NCBI Official Synonym Symbols: | ARHS; RHO6; RHOS |
| NCBI Protein Information: | rho-related GTP-binding protein Rho6 |
| UniProt Protein Name: | Rho-related GTP-binding protein Rho6 |
| UniProt Synonym Protein Names: | Rho family GTPase 1; Rnd1 |
| Protein Family: | Rho-related GTP-binding protein |
| UniProt Gene Name: | RND1 |
 | Western blot analysis of extracts of various cell lines, using RND1 antibody (CAB13705) at 1:3000 dilution. |
 | Immunofluorescence analysis of L929 cells using RND1 Rabbit pAb (CAB13705) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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