Anti-RIPK4 Antibody (CAB8495)
- SKU:
- CAB8495
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-RIPK4 Antibody |
| Antibody SKU: | CAB8495 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A375 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HRPE LPPV CRAR PRAC SHLI RLMQ RCWQ GDPR VRPT FQEI TSET EDLC EKPD DEVK ETAH DLDV KSPP EPRS EVVP ARLK RASA PTFD NDYS LSEL LSQL DSGV SQAV EGPE ELSR SSSE SKLP SSGS GKRL SGVS SVDS AFSS RGSL SLSF EREP STSD LGTT DVQK KKLV DAIV SGDT SKLM KILQ PQDV DLAL DSGA SLLH LAVE AGQE ECAK WLLL NNAN PNLS NRRG STPL HMAV ERRV RGVV ELLL ARKI SVNA KDED QWTA LHFA AQNG DESS T |
| Gene ID: | 54101 |
| Uniprot: | P57078 |
| Cellular Location: | Cytoplasm, Membrane, Peripheral membrane protein |
| Calculated MW: | 86kDa/91kDa |
| Observed MW: | 92KDa |
| Synonyms: | RIPK4, ANKK2, ANKRD3, DIK, NKRD3, PKK, PPS2, RIP4 |
| Background: | The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. |
| UniProt Protein Function: | Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation. |
| NCBI Summary: | The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P57078 |
| NCBI GenInfo Identifier: | 10719883 |
| NCBI Gene ID: | 54101 |
| NCBI Accession: | P57078.1 |
| UniProt Secondary Accession: | P57078,Q96KH0, |
| UniProt Related Accession: | P57078 |
| Molecular Weight: | Calculated: 86kDa; 91kDaObserved: 85kDa |
| NCBI Full Name: | Receptor-interacting serine/threonine-protein kinase 4 |
| NCBI Synonym Full Names: | receptor interacting serine/threonine kinase 4 |
| NCBI Official Symbol: | RIPK4 |
| NCBI Official Synonym Symbols: | DIK; PKK; PPS2; RIP4; ANKK2; NKRD3; ANKRD3; CHANDS |
| NCBI Protein Information: | receptor-interacting serine/threonine-protein kinase 4 |
| UniProt Protein Name: | Receptor-interacting serine/threonine-protein kinase 4 |
| UniProt Synonym Protein Names: | Ankyrin repeat domain-containing protein 3; PKC-delta-interacting protein kinase |
| Protein Family: | Receptor-interacting serine/threonine-protein kinase |
| UniProt Gene Name: | RIPK4 |
 | Western blot analysis of extracts of A375 cells, using RIPK4 Rabbit pAb (CAB8495) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human liver damage using RIPK4 antibody (CAB8495) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using RIPK4 antibody (CAB8495) at dilution of 1:100 (40x lens). |
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