Anti-RIMS2 Antibody (CAB14990)
- SKU:
- CAB14990
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-RIMS2 Antibody |
| Antibody SKU: | CAB14990 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | Jurkat, LO2, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MQFE TLRQ VCNS VLSH FHGV FSSP PNIL QNEL FGQT LNNA RKRS PSVS RDQN RRYD QREE REEY SQYA TSDT AMPR SPSD YADR RSQH EPQF YEDS DHLS YRDS NRRS HRHS KEYI VDDE DVES RDEY ERQR REEE YQSR YRSD PNLA RYPV KPQP YEEQ MRIH AEVS RARH ERRH SDVS LANA DLED SRIS MLRM DRPS RQRS ISER RAAM ENQR SYSM ERTR EAQG PSSY AQRT TNHS PPTP RRSP LPID RPDL RRTD SLRK QHHL DPSS AVRK TKRE KMET MLRN DSLS SDQS ESVR PPPP KPHK SKKG GKMR QISL SSSE EELA STPE YTSC DDVE IESE SVSE KG |
| Gene ID: | 9699 |
| Uniprot: | Q9UQ26 |
| Cellular Location: | Cell junction, Cell membrane, Peripheral membrane protein, presynaptic cell membrane, synapse |
| Calculated MW: | 85kDa/165kDa |
| Observed MW: | 165kDa |
| Synonyms: | RIMS2, OBOE, RAB3IP3, RIM2 |
| Background: | The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. |
| UniProt Code: | Q9UQ26 |
| NCBI GenInfo Identifier: | 41019522 |
| NCBI Gene ID: | 9699 |
| NCBI Accession: | Q9UQ26.2 |
| UniProt Secondary Accession: | Q9UQ26,O43413, Q86XL9, Q8IWV9, Q8IWW1, B3KX91, F8WD47 |
| UniProt Related Accession: | Q9UQ26 |
| Molecular Weight: | 1411 |
| NCBI Full Name: | Regulating synaptic membrane exocytosis protein 2 |
| NCBI Synonym Full Names: | regulating synaptic membrane exocytosis 2 |
| NCBI Official Symbol: | RIMS2 |
| NCBI Official Synonym Symbols: | OBOE; RIM2; RAB3IP3 |
| NCBI Protein Information: | regulating synaptic membrane exocytosis protein 2; RIM 2; nuclear protein; Rab3-interacting protein; RAB3 interacting protein 3; rab-3-interacting protein 3; rab3-interacting molecule 2; rab-3-interacting molecule 2; non-small cell lung cancer RimL3a prot |
| UniProt Protein Name: | Regulating synaptic membrane exocytosis protein 2 |
| UniProt Synonym Protein Names: | Rab-3-interacting molecule 2; RIM 2; Rab-3-interacting protein 3 |
| Protein Family: | Mitochondrial carrier protein |
| UniProt Gene Name: | RIMS2 |
| UniProt Entry Name: | RIMS2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RIMS2 antibody (CAB14990) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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