Anti-RHOBTB2 Antibody (CAB18432)
- SKU:
- CAB18432
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Antibody Name: | Anti-RHOBTB2 Antibody |
Antibody SKU: | CAB18432 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human RHOBTB2. |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Rat lung |
Immunogen: | Recombinant protein of human RHOBTB2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 23221 |
Uniprot: | Q9BYZ6 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 83kDa |
Synonyms: | DBC2, RHOBTB2 |
Background: |
UniProt Protein Function: | RHOBTB2: is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rho; G protein, monomeric Chromosomal Location of Human Ortholog: 8p21.3 Cellular Component: plasma membrane; cytosol Molecular Function:GTP binding Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction |
NCBI Summary: | The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9BYZ6 |
NCBI GenInfo Identifier: | 12667516 |
NCBI Gene ID: | 23221 |
NCBI Accession: | AAG61157.1 |
UniProt Secondary Accession: | Q9BYZ6,O94825, Q8N4A8, Q9BZK6, A8K9Z8, D3DSR8, E9PBU2 E9PEI7, |
UniProt Related Accession: | Q9BYZ6 |
Molecular Weight: | 83,469 Da |
NCBI Full Name: | DBC2 |
NCBI Synonym Full Names: | Rho-related BTB domain containing 2 |
NCBI Official Symbol: | RHOBTB2 |
NCBI Official Synonym Symbols: | DBC2 |
NCBI Protein Information: | rho-related BTB domain-containing protein 2; deleted in breast cancer 2 gene protein; p83 |
UniProt Protein Name: | Rho-related BTB domain-containing protein 2 |
UniProt Synonym Protein Names: | Deleted in breast cancer 2 gene protein; p83 |
UniProt Gene Name: | RHOBTB2 |
UniProt Entry Name: | RHBT2_HUMAN |