Anti-RELT 항체 (CAB15540)

Antibody Name:	Anti-RELT Antibody
Antibody SKU:	CAB15540
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2).

Application:	WB
Recommended Dilution:	WB 1:200 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	Raji, K-562, LO2, Mouse thymus, Mouse brain, Rat thymus, Rat brain

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	STTL WQCP PGEE PDLD PGQG TLCR PCPP GTFS AAWG SSPC QPHA RCSL WRRL EAQV GMAT RDTL CGDC WPGW FGPW GVPR VPCQ PCSW APLG THGC DEWG RRAR RGVE VAAG ASSG GETR QPGN GTRA GGPE ETAA Q
Gene ID:	84957
Uniprot:	Q969Z4
Cellular Location:	Cell membrane, Cytoplasm, Single-pass type I membrane protein
Calculated MW:	46kDa
Observed MW:	47kDa

Synonyms:

RELT, TNFRSF19L, TRLT

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

UniProt Protein Function:	RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family.
UniProt Protein Details:	Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11q13.4 Cellular Component: integral to plasma membrane Molecular Function:tumor necrosis factor receptor activity Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide
NCBI Summary:	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
UniProt Code:	Q969Z4
NCBI GenInfo Identifier:	21264092
NCBI Gene ID:	84957
NCBI Accession:	Q969Z4.1
UniProt Secondary Accession:	Q969Z4,Q86V34, Q96JU1, Q9BUX7,
UniProt Related Accession:	Q969Z4
Molecular Weight:	46,092 Da
NCBI Full Name:	Tumor necrosis factor receptor superfamily member 19L
NCBI Synonym Full Names:	RELT tumor necrosis factor receptor
NCBI Official Symbol:	RELT
NCBI Official Synonym Symbols:	TRLT; TNFRSF19L
NCBI Protein Information:	tumor necrosis factor receptor superfamily member 19L
UniProt Protein Name:	Tumor necrosis factor receptor superfamily member 19L
UniProt Synonym Protein Names:	Receptor expressed in lymphoid tissues
Protein Family:	RELT-like protein
UniProt Gene Name:	RELT
UniProt Entry Name:	TR19L_HUMAN

Western blot analysis of extracts of various cell lines, using RELT antibody (CAB15540) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60S.

Antibodies

RELT Antibody (PACO05549)

RELT Antibody (PACO11800)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)