Anti-RDH11 Antibody (CAB18454)
- SKU:
- CAB18454
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-RDH11 Antibody |
| Antibody SKU: | CAB18454 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RDH11. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | PC-3, HepG2 |
| Immunogen: | Recombinant protein of human RDH11. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 51109 |
| Uniprot: | Q8TC12 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 35kDa |
 | Western blot - RDH11 Rabbit pAb (CAB18454) |
| Synonyms: | ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, RDJCSS, SCALD, SDR7C1, RDH11 |
| Background: |
| UniProt Protein Function: | RDH11: Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; Oxidoreductase; EC 1.1.1.300 Chromosomal Location of Human Ortholog: 14q24.1 Cellular Component: endoplasmic reticulum membrane; photoreceptor inner segment; integral to membrane; intracellular Molecular Function:retinol dehydrogenase activity Biological Process: phototransduction, visible light; retinal metabolic process; retinol metabolic process; adaptation of rhodopsin mediated signaling; retinoid metabolic process Disease: Retinal Dystrophy, Juvenile Cataracts, And Short Stature Syndrome |
| NCBI Summary: | The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011] |
| UniProt Code: | Q8TC12 |
| NCBI GenInfo Identifier: | 90110515 |
| NCBI Gene ID: | 51109 |
| NCBI Accession: | ABD90542.1 |
| UniProt Secondary Accession: | Q8TC12,Q6IAH5, Q9NRW0, Q9Y391, A6NDK3, A8K062, B2RB26 B4DDW0, |
| UniProt Related Accession: | Q8TC12 |
| Molecular Weight: | 35,386 Da |
| NCBI Full Name: | retinol dehydrogenase 11, partial |
| NCBI Synonym Full Names: | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| NCBI Official Symbol: | RDH11 |
| NCBI Official Synonym Symbols: | MDT1; CGI82; PSDR1; RALR1; SCALD; ARSDR1; HCBP12; SDR7C1 |
| NCBI Protein Information: | retinol dehydrogenase 11; retinal reductase 1; HCV core-binding protein HCBP12; prostate short-chain dehydrogenase reductase 1; prostate short-chain dehydrogenase/reductase 1; short chain dehydrogenase/reductase family 7C, member 1; androgen-regulated short-chain dehydrogenase/reductase 1 |
| UniProt Protein Name: | Retinol dehydrogenase 11 |
| UniProt Synonym Protein Names: | Androgen-regulated short-chain dehydrogenase/reductase 1; HCV core-binding protein HCBP12; Prostate short-chain dehydrogenase/reductase 1; Retinal reductase 1 |
| Protein Family: | Retinol dehydrogenase |
| UniProt Gene Name: | RDH11 |
| UniProt Entry Name: | RDH11_HUMAN |
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