Anti-RCN2 Antibody (CAB19943)[KO Validated]

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SKU:
CAB19943
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-RCN2 Antibody [KO Validated]
Antibody SKU:CAB19943
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human RCN2.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T
Immunogen:Recombinant protein of human RCN2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5955
Uniprot:Q14257
Cellular Location:Endoplasmic reticulum lumen
Calculated MW:36kDa/39kDa
Observed MW:47KDa
Anti-RCN2 Antibody [KO Validated] (CAB19943)Western blot analysis of extracts from normal (control) and RCN2 knockout (KO) 293T cells, using RCN2 antibody (CAB19943) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Synonyms:RCN2, E6BP, ERC-55, ERC55, TCBP49
Background:The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:RCN2: Not known. Binds calcium. Belongs to the CREC family.
UniProt Protein Details:

Protein type:Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum; nucleolus

Molecular Function:protein binding; calcium ion binding

NCBI Summary:The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
UniProt Code:Q14257
NCBI GenInfo Identifier:2493460
NCBI Gene ID:5955
NCBI Accession:Q14257.1
UniProt Related Accession:Q14257
Molecular Weight:
NCBI Full Name:Reticulocalbin-2
NCBI Synonym Full Names:reticulocalbin 2
NCBI Official Symbol:RCN2  
NCBI Official Synonym Symbols:E6BP; ERC55; ERC-55; TCBP49  
NCBI Protein Information:reticulocalbin-2
UniProt Protein Name:Reticulocalbin-2
UniProt Synonym Protein Names:Calcium-binding protein ERC-55; E6-binding protein; E6BP
Protein Family:Reticulocalbin
UniProt Gene Name:RCN2  
UniProt Entry Name:RCN2_HUMAN

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