Anti-RBP7 Antibody (CAB15939)
- SKU:
- CAB15939
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-RBP7 Antibody |
| Antibody SKU: | CAB15939 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human RBP7 (NP_443192.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse heart, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human RBP7 (NP_443192.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPAD LSGT WTLL SSDN FEGY MLAL GIDF ATRK IAKL LKPQ KVIE QNGD SFTI HTNS SLRN YFVK FKVG EEFD EDNR GLDN RKCK SLVI WDND RLTC IQKG EKKN RGWT HWIE GDKL HLEM FCEG QVCK QTFQ RA |
| Gene ID: | 116362 |
| Uniprot: | Q96R05 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 15kDa |
| Observed MW: | 15kDa |
| Synonyms: | RBP7, CRABP4, CRBP4, CRBPIV |
| Background: | The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. |
| UniProt Protein Function: | RBP7: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1p36.22 Molecular Function:protein binding |
| NCBI Summary: | Due to its chemical instability and low solubility in aqueous solution, vitamin A requires cellular retinol-binding proteins (CRBPs), such as RBP7, for stability, internalization, intercellular transfer, homeostasis, and metabolism.[supplied by OMIM, May 2004] |
| UniProt Code: | Q96R05 |
| NCBI GenInfo Identifier: | 20139582 |
| NCBI Gene ID: | 116362 |
| NCBI Accession: | Q96R05.1 |
| UniProt Secondary Accession: | Q96R05,Q5SWJ4, B2R517, |
| UniProt Related Accession: | Q96R05 |
| Molecular Weight: | 15,536 Da |
| NCBI Full Name: | Retinoid-binding protein 7 |
| NCBI Synonym Full Names: | retinol binding protein 7 |
| NCBI Official Symbol: | RBP7 |
| NCBI Official Synonym Symbols: | CRBP4; CRBPIV |
| NCBI Protein Information: | retinoid-binding protein 7 |
| UniProt Protein Name: | Retinoid-binding protein 7 |
| UniProt Synonym Protein Names: | Cellular retinoic acid-binding protein 4; CRABP4; CRBP4; Cellular retinoic acid-binding protein IV; CRABP-IV |
| Protein Family: | Retinoid-binding protein |
| UniProt Gene Name: | RBP7 |
| UniProt Entry Name: | RET7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RBP7 antibody (CAB15939) at 1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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