Anti-RBP2 Antibody (CAB6717)
- SKU:
- CAB6717
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-RBP2 Antibody |
| Antibody SKU: | CAB6717 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human RBP2 (NP_004155.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse small intestine, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human RBP2 (NP_004155.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTRD QNGT WEME SNEN FEGY MKAL DIDF ATRK IAVR LTQT KVID QDGD NFKT KTTS TFRN YDVD FTVG VEFD EYTK SLDN RHVK ALVT WEGD VLVC VQKG EKEN RGWK QWIE GDKL YLEL TCGD QVCR QVFK KK |
| Gene ID: | 5948 |
| Uniprot: | P50120 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 15kDa |
| Observed MW: | 15-17kDa |
| Synonyms: | RBP2, CRABP-II, CRBP2, CRBPII, RBPC2 |
| Background: | This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. |
| UniProt Protein Function: | RBP2: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q23 Cellular Component: cytosol Molecular Function:retinoid binding Biological Process: epidermis development; retinoid metabolic process |
| NCBI Summary: | This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P50120 |
| NCBI GenInfo Identifier: | 62297500 |
| NCBI Gene ID: | 5948 |
| NCBI Accession: | P50120.3 |
| UniProt Secondary Accession: | P50120,Q6ISQ9, Q6ISS7, A8K7G3, |
| UniProt Related Accession: | P50120 |
| Molecular Weight: | 16kDa |
| NCBI Full Name: | Retinol-binding protein 2 |
| NCBI Synonym Full Names: | retinol binding protein 2 |
| NCBI Official Symbol: | RBP2 |
| NCBI Official Synonym Symbols: | CRBP2; RBPC2; CRBPII; CRABP-II |
| NCBI Protein Information: | retinol-binding protein 2 |
| UniProt Protein Name: | Retinol-binding protein 2 |
| UniProt Synonym Protein Names: | Cellular retinol-binding protein II; CRBP-II |
| Protein Family: | RNA-binding protein |
| UniProt Gene Name: | RBP2 |
 | Western blot analysis of extracts of various cell lines, using RBP2 antibody (CAB6717) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded human liver damage using RBP2 antibody (CAB6717) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using RBP2 antibody (CAB6717) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat brain using RBP2 antibody (CAB6717) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of MCF-7 cells using RBP2 antibody (CAB6717). Blue: DAPI for nuclear staining. |
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