Anti-RBM3 Antibody (CAB19967)[KO Validated]
- SKU:
- CAB19967
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Antibody Name: | Anti-RBM3 Antibody [KO Validated] |
Antibody SKU: | CAB19967 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human RBM3. |
Application: | WB IHC IF |
Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T |
Immunogen: | Recombinant protein of human RBM3. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 5935 |
Uniprot: | P98179 |
Cellular Location: | Cell projection, Cytoplasm, Nucleus, dendrite |
Calculated MW: | 17kDa |
Observed MW: | 17KDa |
Synonyms: | RBM3, IS1-RNPL, RNPL |
Background: | This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. |
UniProt Protein Function: | RBM3: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation. |
UniProt Protein Details: | Protein type:Translation; RNA-binding; Ribosomal; RNA processing Chromosomal Location of Human Ortholog: Xp11.2 Cellular Component: cytoplasm; dendrite; nucleus; large ribosomal subunit Molecular Function:protein binding; RNA binding; nucleotide binding; ribosomal large subunit binding Biological Process: RNA processing; regulation of translation; miRNA-mediated gene silencing, production of miRNAs; positive regulation of translation; translation; response to cold |
NCBI Summary: | This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008] |
UniProt Code: | P98179 |
NCBI GenInfo Identifier: | 1710620 |
NCBI Gene ID: | 5935 |
NCBI Accession: | P98179.1 |
UniProt Related Accession: | P98179 |
Molecular Weight: | 157 |
NCBI Full Name: | Putative RNA-binding protein 3 |
NCBI Synonym Full Names: | RNA binding motif (RNP1, RRM) protein 3 |
NCBI Official Symbol: | RBM3 |
NCBI Official Synonym Symbols: | RNPL; IS1-RNPL |
NCBI Protein Information: | putative RNA-binding protein 3; RNA-binding motif protein 3 |
UniProt Protein Name: | Putative RNA-binding protein 3 |
UniProt Synonym Protein Names: | RNA-binding motif protein 3; RNPL |
Protein Family: | RNA-binding protein |
UniProt Gene Name: | RBM3 |
UniProt Entry Name: | RBM3_HUMAN |