Anti-RARS2 Antibody (CAB8503)
- SKU:
- CAB8503
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-RARS2 Antibody |
| Antibody SKU: | CAB8503 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-340 of human RARS2 (NP_064716.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | K-562, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-340 of human RARS2 (NP_064716.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LNLP PENL ITSI SAVP ISQK EEVA DFQL SVDS LLEK DNDH SRPD IQVQ AKRL AEKL RCDT VVSE ISTG QRTV NFKI NREL LTKT VLQQ VIED GSKY GLKS ELFS GLPQ KKIV VEFS SPNV AKKF HVGH LRST IIGN FIAN LKEA LGHQ VIRI NYLG DWGM QFGL LGTG FQLF GYEE KLQS NPLQ HLFE VYVQ VNKE AADD KSVA KAAQ EFFQ RLEL GDVQ ALSL WQKF RDLS IEEY IRVY KRLG VYFD EYSG ESFY REKS QEVL KLLE SKGL LLKT IKGT AVVD LSGN GDPS SICT VMRS DGTS LYAT RDLA AAID RMDK YNFD |
| Gene ID: | 57038 |
| Uniprot: | Q5T160 |
| Cellular Location: | Mitochondrion matrix |
| Calculated MW: | 65kDa |
| Observed MW: | 58kDa |
| Synonyms: | RARS2, ArgRS, DALRD2, PCH6, PRO1992, RARSL |
| Background: | This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants. |
| NCBI Summary: | This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q5T160 |
| NCBI GenInfo Identifier: | 197100773 |
| NCBI Gene ID: | 57038 |
| NCBI Accession: | NP_064716.2 |
| UniProt Secondary Accession: | Q5T160,Q96FU5, Q9H8K8, B2RDT7, |
| UniProt Related Accession: | Q5T160 |
| Molecular Weight: | 65,505 Da |
| NCBI Full Name: | probable arginine--tRNA ligase, mitochondrial isoform 1 |
| NCBI Synonym Full Names: | arginyl-tRNA synthetase 2, mitochondrial |
| NCBI Official Symbol: | RARS2 |
| NCBI Official Synonym Symbols: | PCH6; ArgRS; RARSL; DALRD2; PRO1992 |
| NCBI Protein Information: | probable arginine--tRNA ligase, mitochondrial |
| UniProt Protein Name: | Probable arginine--tRNA ligase, mitochondrial |
| UniProt Synonym Protein Names: | Arginyl-tRNA synthetase; ArgRS |
| Protein Family: | Probable arginine--tRNA ligase |
| UniProt Gene Name: | RARS2 |
 | Western blot analysis of extracts of various cell lines, using RARS2 antibody (CAB8503) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse stomach using RARS2 antibody (CAB8503) at dilution of 1:100 (40x lens). |
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