Anti-RanBP9 Antibody (CAB19238)
- SKU:
- CAB19238
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RANBP9
- BPM-L
- BPM90
- RANBPM
- RanBP7
- ran-binding protein 9
Frequently bought together:
Description
| Product Name: | RanBP9 Rabbit mAb |
| Product Code: | CAB19238 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | RANBP9, BPM-L, BPM90, RANBPM, RanBP7, ran-binding protein 9 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RanBP9 . |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | C2C12, RD, C6, Mouse testis, Rat testis |
| Immunogen: | Recombinant protein of human RanBP9 . |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10048 |
| Uniprot: | Q96S59 |
| Cellular Location: | Cytoplasm, Nucleus, cytosol |
| Calculated MW: | 91kDa |
| Observed MW: | 80KDa/91KDa |
| UniProt Protein Function: | RANBP9: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. Belongs to the RANBP9/10 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Adaptor/scaffold; GAPs; GAPs, Ras Chromosomal Location of Human Ortholog: 6p23 Cellular Component: microtubule associated complex; nucleus; cytosol Molecular Function:protein binding; enzyme binding; Ran GTPase binding Biological Process: axon guidance; protein complex assembly; microtubule nucleation |
| NCBI Summary: | This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96S59 |
| NCBI GenInfo Identifier: | 61215334 |
| NCBI Gene ID: | 10048 |
| NCBI Accession: | Q96S59.1 |
| UniProt Related Accession: | Q96S59 |
| Molecular Weight: | 42kDa |
| NCBI Full Name: | Ran-binding protein 9 |
| NCBI Synonym Full Names: | RAN binding protein 9 |
| NCBI Official Symbol: | RANBP9 |
| NCBI Official Synonym Symbols: | BPM-L; BPM90; RANBPM; RanBP7 |
| NCBI Protein Information: | ran-binding protein 9 |
| UniProt Protein Name: | Ran-binding protein 9 |
| UniProt Synonym Protein Names: | BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7 |
| Protein Family: | Ran-binding protein |
| UniProt Gene Name: | RANBP9 |
| UniProt Entry Name: | RANB9_HUMAN |
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