Anti-RABGGTB Antibody (CAB15310)
- SKU:
- CAB15310
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-RABGGTB Antibody |
| Antibody SKU: | CAB15310 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human RABGGTB (NP_004573.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, HeLa, HepG2, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human RABGGTB (NP_004573.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGTP QKDV IIKS DAPD TLLL EKHA DYIA SYGS KKDD YEYC MSEY LRMS GIYW GLTV MDLM GQLH RMNR EEIL AFIK SCQH ECGG ISAS IGHD PHLL YTLS AVQI LTLY DSIN VIDV NKVV EYVK GLQK EDGS FAGD IWGE IDTR FSFC AVAT LALL GKLD AINV EKAI EFVL SCMN FDGG FGCR PGSE SHAG QIYC CTGF LAIT SQLH QVNS DLLG WWLC ERQL PSGG LNGR PEKL PDVC YSWW VLAS LKII GRLH WIDR EKLR NFIL ACQD EETG GFAD RPGD MVDP FHTL FGIA GLSL LGEE QIKP VNPV FCMP EEVL QRVN VQPE LVS |
| Gene ID: | 5876 |
| Uniprot: | P53611 |
| Cellular Location: | |
| Calculated MW: | 36kDa |
| Observed MW: | 37kDa |
| Synonyms: | RABGGTB, GGTB |
| Background: | This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. |
| NCBI Summary: | This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013] |
| UniProt Code: | P53611 |
| NCBI GenInfo Identifier: | 18088527 |
| NCBI Gene ID: | 5876 |
| NCBI Accession: | BC020790 |
| UniProt Secondary Accession: | P53611,Q92697, |
| UniProt Related Accession: | P53611 |
| Molecular Weight: | 36,924 Da |
| NCBI Full Name: | Homo sapiens Rab geranylgeranyltransferase, beta subunit, mRNA |
| NCBI Synonym Full Names: | Rab geranylgeranyltransferase beta subunit |
| NCBI Official Symbol: | RABGGTB |
| NCBI Official Synonym Symbols: | GGTB |
| NCBI Protein Information: | geranylgeranyl transferase type-2 subunit beta |
| UniProt Protein Name: | |
| Protein Family: | Geranylgeranyl transferase |
| UniProt Gene Name: |
 | Western blot analysis of extracts of various cell lines, using RABGGTB antibody (CAB15310) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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