Anti-RAB3IP Antibody (CAB8094)

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SKU:
CAB8094
Product type:
Antibody
Application:
WB
Application:
IHC
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:RAB3IP Rabbit Polyclonal Antibody
Antibody SKU:CAB8094
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB3IP (NP_071901.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, A-549, 293T, Mouse heart, Mouse kidney, Mouse brain, Mouse liver, Rat brain, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human RAB3IP (NP_071901.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAND PLEG FHEV NLAS PTSP DLLG VYES GTQE QTTS PSVI YRPH PSAL SSVP IQAN ALDV SELP TQPV YSSP RRLN CAEI SSIS FHVT DPAP CSTS GVTA GLTK LTTR KDNY NAER EFLQ GATI TEAC DGSD DIFG LSTD SLSR LRSP SV
Gene ID:117177
Uniprot:Q96QF0
Cellular Location:Cell projection, Cytoplasm, Nucleus, cytoskeleton, lamellipodium
Calculated MW:28kDa/33-53kDa
Observed MW:53kDa
Synonyms:RAB3IP, RABIN3, RABIN8
Background:
UniProt Protein Function:RAB3IP: Guanine nucleotide exchange factor for RAB8A. Mediates the release of GDP from RAB8A but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC2 family. 8 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GEF; GEF, Rab

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: cytosol; nucleus

Molecular Function:protein binding; Rab guanyl-nucleotide exchange factor activity

Biological Process: protein targeting to membrane

UniProt Code:Q96QF0
NCBI GenInfo Identifier:71152025
NCBI Gene ID:117177
NCBI Accession:Q96QF0.1
UniProt Secondary Accession:Q96QF0,Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9 Q96QF1, Q9H673, B7WPJ6,
UniProt Related Accession:Q96QF0
Molecular Weight:53kDa
NCBI Full Name:Rab-3A-interacting protein
NCBI Synonym Full Names:RAB3A interacting protein
NCBI Official Symbol:RAB3IP  
NCBI Official Synonym Symbols:RABIN3; RABIN8  
NCBI Protein Information:rab-3A-interacting protein
UniProt Protein Name:Rab-3A-interacting protein
UniProt Synonym Protein Names:Rabin-3; SSX2-interacting protein
Protein Family:Rab-3A-interacting protein
UniProt Gene Name:RAB3IP  
Anti-RAB3IP Polyclonal Antibody (CAB8094)Western blot analysis of extracts of various cell lines, using RAB3IP antibody (CAB8094) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-RAB3IP Polyclonal Antibody (CAB8094)Immunohistochemistry of paraffin-embedded mouse brain using RAB3IP antibody (CAB8094) at dilution of 1:100 (40x lens).
Anti-RAB3IP Polyclonal Antibody (CAB8094)Immunohistochemistry of paraffin-embedded rat brain using RAB3IP antibody (CAB8094) at dilution of 1:100 (40x lens).
Anti-RAB3IP Polyclonal Antibody (CAB8094)Immunohistochemistry of paraffin-embedded human lung cancer using RAB3IP antibody (CAB8094) at dilution of 1:100 (40x lens).
Anti-RAB3IP Polyclonal Antibody (CAB8094)Immunohistochemistry of paraffin-embedded human stomach using RAB3IP antibody (CAB8094) at dilution of 1:100 (40x lens).

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