Anti-RAB1A Antibody (CAB14663)
- SKU:
- CAB14663
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
| Antibody Name: | Anti-RAB1A Antibody |
| Antibody SKU: | CAB14663 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB1A (NP_004152.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse liver, Mouse lung |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB1A (NP_004152.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSSM NPEY DYLF KLLL IGDS GVGK SCLL LRFA DDTY TESY ISTI GVDF KIRT IELD GKTI KLQI WDTA GQER FRTI TSSY YRGA HGII VVYD VTDQ ESFN |
| Gene ID: | 5861 |
| Uniprot: | P62820 |
| Cellular Location: | Cytoplasm, Early endosome, Endoplasmic reticulum, Golgi apparatus, Melanosome, Membrane, cytosol |
| Calculated MW: | 13kDa/15kDa/22kDa |
| Observed MW: | 23kDa |
| Synonyms: | RAB1A, RAB1, YPT1 |
| Background: | This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. |
| UniProt Protein Function: | RAB1A: Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rab; G protein Chromosomal Location of Human Ortholog: 2p14 Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; early endosome; melanosome; cytosol Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding Biological Process: ER to Golgi vesicle-mediated transport; cell migration; endocytosis; virus assembly; melanosome transport; vesicle-mediated transport; growth hormone secretion; intracellular protein transport; defense response to bacterium; vesicle transport along microtubule; autophagy; cilium biogenesis; mitotic cell cycle; Rab protein signal transduction; Golgi organization and biogenesis; autophagic vacuole formation |
| NCBI Summary: | This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008] |
| UniProt Code: | P62820 |
| NCBI GenInfo Identifier: | 51338603 |
| NCBI Gene ID: | 5861 |
| NCBI Accession: | P62820.3 |
| UniProt Related Accession: | P62820 |
| Molecular Weight: | |
| NCBI Full Name: | Ras-related protein Rab-1A |
| NCBI Synonym Full Names: | RAB1A, member RAS oncogene family |
| NCBI Official Symbol: | RAB1A |
| NCBI Official Synonym Symbols: | RAB1; YPT1 |
| NCBI Protein Information: | ras-related protein Rab-1A |
| UniProt Protein Name: | Ras-related protein Rab-1A |
| UniProt Synonym Protein Names: | YPT1-related protein |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB1A |
| UniProt Entry Name: | RAB1A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RAB1A antibody (CAB14663) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunofluorescence analysis of L929 cells using RAB1A antibody (CAB14663) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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