| UniProt Protein Function: | RAB14: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor. |
| UniProt Protein Details: | Protein type:G protein; G protein, monomeric; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 9q33.2 Cellular Component: cilium; cytoplasmic vesicle membrane; cytosol; early endosome; early endosome membrane; Golgi stack; intracellular; intracellular membrane-bound organelle; late endosome; lysosomal membrane; lysosome; nuclear envelope-endoplasmic reticulum network; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; recycling endosome; recycling endosome membrane; rough endoplasmic reticulum; trans-Golgi network transport vesicle Molecular Function:GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding Biological Process: embryonic development; endocytic recycling; fibroblast growth factor receptor signaling pathway; Golgi to endosome transport; neutrophil degranulation; phosphatidylinositol biosynthetic process; regulation of endocytosis; regulation of protein localization |
| NCBI Summary: | RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009] |
| UniProt Code: | P61106 |
| NCBI GenInfo Identifier: | 85700392 |
| NCBI Gene ID: | 51552 |
| NCBI Accession: | P61106.4 |
| UniProt Secondary Accession: | P61106,P35287, Q5JVD4, Q6Q7K5, Q969L0, Q9UI11, B3KR31 |
| UniProt Related Accession: | P61106 |
| Molecular Weight: | 24kDa |
| NCBI Full Name: | Ras-related protein Rab-14 |
| NCBI Synonym Full Names: | RAB14, member RAS oncogene family |
| NCBI Official Symbol: | RAB14 |
| NCBI Official Synonym Symbols: | FBP; RAB-14 |
| NCBI Protein Information: | ras-related protein Rab-14 |
| UniProt Protein Name: | Ras-related protein Rab-14 |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB14 |
