Anti-PVALB Antibody (CAB13538)
- SKU:
- CAB13538
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PVALB Antibody |
| Antibody SKU: | CAB13538 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human PVALB (NP_002845.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse skeletal muscle, Rat skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human PVALB (NP_002845.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSMT DLLN AEDI KKAV GAFS ATDS FDHK KFFQ MVGL KKKS ADDV KKVF HMLD KDKS GFIE EDEL GFIL KGFS PDAR DLSA KETK MLMA AGDK DGDG KIGV DEFS TLVA ES |
| Gene ID: | 5816 |
| Uniprot: | P20472 |
| Cellular Location: | |
| Calculated MW: | 12kDa |
| Observed MW: | 13kDa |
| Synonyms: | D22S749, Parvalbumin, PVALB, parvalbumin |
| Background: | The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: protein complex; cell soma; axon; cytoplasm; nucleus Molecular Function:protein homodimerization activity; protein heterodimerization activity; calcium ion binding Biological Process: cytosolic calcium ion homeostasis |
| NCBI Summary: | The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P20472 |
| NCBI GenInfo Identifier: | 131100 |
| NCBI Gene ID: | 5816 |
| NCBI Accession: | P20472.2 |
| UniProt Secondary Accession: | P20472,P78378, Q4VB78, Q5R3Q9, B2R4H7, |
| UniProt Related Accession: | P20472 |
| Molecular Weight: | 110 |
| NCBI Full Name: | Parvalbumin alpha |
| NCBI Synonym Full Names: | parvalbumin |
| NCBI Official Symbol: | PVALB |
| NCBI Official Synonym Symbols: | D22S749 |
| NCBI Protein Information: | parvalbumin alpha |
| UniProt Protein Name: | Parvalbumin alpha |
| Protein Family: | Parvalbumin |
| UniProt Gene Name: | PVALB |
| UniProt Entry Name: | PRVA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PVALB antibody (CAB13538) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human esophageal using PVALB Rabbit pAb (CAB13538) at dilution of 1:100 (40x lens). |
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