Anti-PTPN23 Antibody (CAB4595)
- SKU:
- CAB4595
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PTPN23
- HD-PTP
- HDPTP
- PTP-TD14
Frequently bought together:
Description
| Product Name: | PTPN23 Rabbit pAb |
| Product Code: | CAB4595 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | PTPN23, HD-PTP, HDPTP, PTP-TD14 |
| Applications: | WB, IHC |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_056281.1). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse eye, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_056281.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DSNR VVLR SGKD DYIN ASCV EGLS PYCP PLVA TQAP LPGT AADF WLMV HEQK VSVI VMLV SEAE MEKQ KVAR YFPT ERGQ PMVH GALS LALS SVRS TETH VERV LSLQ FRDQ SLKR SLVH LHFP TWPE LGLP DSPS NLLR FIQE VHAH YLHQ RPLH TPII VHCS SGVG RTGA FALL YAAV QEVE AGNG IPEL PQLV RRMR QQRK HMLQ EKLH LRFC YEAV V |
| Gene ID: | 25930 |
| Uniprot: | Q9H3S7 |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Early endosome, Endosome, Nucleus, cilium basal body, cytoskeleton |
| Calculated MW: | 178kDa |
| Observed MW: | 179kDa |
| UniProt Protein Function: | PTPN23: May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. |
| UniProt Protein Details: | Protein type:EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: nucleoplasm; cytoplasmic membrane-bound vesicle; cytoplasm; early endosome; nucleus; endosome Molecular Function:protein binding; protein tyrosine phosphatase activity; protein kinase binding Biological Process: protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body pathway |
| UniProt Code: | Q9H3S7 |
| NCBI GenInfo Identifier: | 68053318 |
| NCBI Gene ID: | 25930 |
| NCBI Accession: | Q9H3S7.1 |
| UniProt Secondary Accession: | Q9H3S7,Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4 A8K0D7, |
| UniProt Related Accession: | Q9H3S7 |
| Molecular Weight: | 1636 |
| NCBI Full Name: | Tyrosine-protein phosphatase non-receptor type 23 |
| NCBI Synonym Full Names: | protein tyrosine phosphatase, non-receptor type 23 |
| NCBI Official Symbol: | PTPN23 |
| NCBI Official Synonym Symbols: | HDPTP; HD-PTP; PTP-TD14 |
| NCBI Protein Information: | tyrosine-protein phosphatase non-receptor type 23; protein tyrosine phosphatase TD14; His-domain protein tyrosine phosphatase; his domain-containing protein tyrosine phosphatase |
| UniProt Protein Name: | Tyrosine-protein phosphatase non-receptor type 23 |
| UniProt Synonym Protein Names: | His domain-containing protein tyrosine phosphatase; HD-PTP; Protein tyrosine phosphatase TD14; PTP-TD14 |
| Protein Family: | Tyrosine-protein phosphatase non-receptor |
| UniProt Gene Name: | PTPN23 |
| UniProt Entry Name: | PTN23_HUMAN |
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