Anti-PTPMT1 Antibody (CAB8594)
- SKU:
- CAB8594
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-PTPMT1 Antibody |
| Antibody SKU: | CAB8594 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PTPMT1 (NP_783859.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PTPMT1 (NP_783859.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAT ALLE AGLA RVLF YPTL LYTL FRGK VPGR AHRD WYHR IDPT VLLG ALPL RSLT RQLV QDEN VRGV ITMN EEYE TRFL CNSS QEWK RLGV EQLR LSTV DMTG IPTL DNLQ KGVQ FALK YQSL GQCV YVHC KAGR SRSA TMVA AYLI QVHK WSPE EAVR AIAK IRSY IHIR PGQL DVLK EFHK QITA RATK DGTF VISK T |
| Gene ID: | 114971 |
| Uniprot: | Q8WUK0 |
| Cellular Location: | Mitochondrion inner membrane |
| Calculated MW: | 15kDa/16kDa/22kDa |
| Observed MW: | 23kDa |
| Synonyms: | PTPMT1, DUSP23, MOSP, PLIP, PNAS-129 |
| Background: |
| UniProt Protein Function: | PTPMT1: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.1.3.16; EC 3.1.3.27; EC 3.1.3.48; Mitochondrial; Phosphatase, lipid; Protein phosphatase, dual-specificity Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: mitochondrion; nucleus Molecular Function:phosphatidylglycerophosphatase activity; phosphoinositide 5-phosphatase activity; protein binding Biological Process: cardiolipin biosynthetic process |
| UniProt Code: | Q8WUK0 |
| NCBI GenInfo Identifier: | 221218988 |
| NCBI Gene ID: | 114971 |
| NCBI Accession: | NP_001137456.1 |
| UniProt Secondary Accession: | Q8WUK0,Q7Z557, Q96CR2, Q9BXV8, E9PAT8, |
| UniProt Related Accession: | Q8WUK0 |
| Molecular Weight: | 35.9kD |
| NCBI Full Name: | phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform 2 |
| NCBI Synonym Full Names: | protein tyrosine phosphatase, mitochondrial 1 |
| NCBI Official Symbol: | PTPMT1 |
| NCBI Official Synonym Symbols: | MOSP; PLIP; DUSP23; PNAS-129 |
| NCBI Protein Information: | phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 |
| UniProt Protein Name: | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 |
| UniProt Synonym Protein Names: | PTEN-like phosphatase; Phosphoinositide lipid phosphatase; Protein-tyrosine phosphatase mitochondrial 1 (EC:3.1.3.16, EC:3.1.3.48) |
| Protein Family: | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase |
| UniProt Gene Name: | PTPMT1 |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
