Anti-PSMG1 Antibody (CAB15339)
- SKU:
- CAB15339
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PSMG1 Antibody |
| Antibody SKU: | CAB15339 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human PSMG1 (NP_003711.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human PSMG1 (NP_003711.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAT FFGE VVKA PCRA GTED EEEE EEGR RETP EDRE VRLQ LARK REVR LLRR QTKT SLEV SLLE KYPC SKFI IAIG NNAV AFLS SFVM NSGV WEEV GCAK LWNE WCRT TDTT HLSS TEAF CVFY HLKS NPSV FLCQ CSCY VAED QQYQ WLEK VFGS CPRK NMQI TILT CRHV TDYK TSES TGSL PSPF LRAL KTQN FKDS ACCP LLEQ PNIV HDLP AAVL SYCQ VWKI PAIL YLCY TDVM KLDL ITVE AFKP ILST RSLK GLVK NIPQ STEI LKKL MTTN EIQS NIYT |
| Gene ID: | 8624 |
| Uniprot: | O95456 |
| Cellular Location: | Cytoplasm, Endoplasmic reticulum |
| Calculated MW: | 30kDa/32kDa |
| Observed MW: | 33kDa |
| Synonyms: | PSMG1, C21LRP, DSCR2, LRPC21, PAC-1, PAC1 |
| Background: |
| UniProt Protein Function: | DSCR2: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Belongs to the PSMG1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum; cytoplasm; nucleus Molecular Function:protein binding Biological Process: granule cell precursor proliferation; proteasome assembly |
| UniProt Code: | O95456 |
| NCBI GenInfo Identifier: | 4505023 |
| NCBI Gene ID: | 8624 |
| NCBI Accession: | NP_003711.1 |
| UniProt Secondary Accession: | O95456,Q6FHA3, Q6FHD3, Q6S713, B5BUN2, |
| UniProt Related Accession: | O95456 |
| Molecular Weight: | 30,288 Da |
| NCBI Full Name: | proteasome assembly chaperone 1 isoform a |
| NCBI Synonym Full Names: | proteasome assembly chaperone 1 |
| NCBI Official Symbol: | PSMG1 |
| NCBI Official Synonym Symbols: | PAC1; DSCR2; PAC-1; C21LRP; LRPC21 |
| NCBI Protein Information: | proteasome assembly chaperone 1 |
| UniProt Protein Name: | Proteasome assembly chaperone 1 |
| UniProt Synonym Protein Names: | Chromosome 21 leucine-rich protein; C21-LRP; Down syndrome critical region protein 2 |
| Protein Family: | Proteasome assembly chaperone |
| UniProt Gene Name: | PSMG1 |
| UniProt Entry Name: | PSMG1_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using PSMG1 antibody (CAB15339) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 5s. |
 | Immunohistochemistry of paraffin-embedded rat spleen using PSMG1 antibody (CAB15339) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human appendix using PSMG1 antibody (CAB15339) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse spleen using PSMG1 antibody (CAB15339) at dilution of 1:100 (40x lens). |
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