Anti-PSIP1 Antibody (CAB18037)[KO Validated]
- SKU:
- CAB18037
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Antibody Name: | Anti-PSIP1 Antibody [KO Validated] |
Antibody SKU: | CAB18037 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | NMLK GQHE KEAA DRKR KQEE QMET EQQN KDEG KKPE VKKV EKKR ETSM DSRL QRIH AEIK NSLK IDNL DVNR CIEA LDEL ASLQ VTMQ QAQK HTEM ITTL KKIR RFKV SQVI MEKS TMLY NKFK NMFL VGEG DSVI TQVL NKSL AEQR QHEE ANKT KDQG KKGP NKKL EKEQ TGSK TLNG GSDA QDGN QPQH NGES NEDS KDNH EAST KKKP SSEE RETE ISLK DSTL DN |
Gene ID: | 11168 |
Uniprot: | O75475 |
Cellular Location: | Nucleus |
Calculated MW: | 37kDa/60kDa |
Observed MW: | 75kDa |
Synonyms: | PSIP1, DFS70, LEDGF, PAIP, PSIP2, p52, p75 |
Background: |
UniProt Protein Function: | Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. |
UniProt Code: | O75475 |
NCBI GenInfo Identifier: | 68565853 |
NCBI Gene ID: | 11168 |
NCBI Accession: | O75475.1 |
UniProt Secondary Accession: | O75475,O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6 D3DRI9, |
UniProt Related Accession: | O75475 |
Molecular Weight: | 76; 51; 45 kDa |
NCBI Full Name: | PC4 and SFRS1-interacting protein |
NCBI Synonym Full Names: | PC4 and SFRS1 interacting protein 1 |
NCBI Official Symbol: | PSIP1 |
NCBI Official Synonym Symbols: | p52; p75; PAIP; DFS70; LEDGF; PSIP2 |
NCBI Protein Information: | PC4 and SFRS1-interacting protein |
UniProt Protein Name: | PC4 and SFRS1-interacting protein |
UniProt Synonym Protein Names: | CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; Transcriptional coactivator p75/p52 |
Protein Family: | PC4 and SFRS1-interacting protein |
UniProt Gene Name: | PSIP1 |