Anti-Prostatic Acid Phosphatase (ACPP) Antibody (CAB4138)

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SKU:
CAB4138
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
5'-NT
ACP-3
ACP3
Frequently bought together:

Description

Product Name:Prostatic Acid Phosphatase (ACPP) Rabbit mAb
Product Code:CAB4138
Size:20uL, 50uL, 100uL
Synonyms:5'-NT, ACP-3, ACP3
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Prostatic Acid Phosphatase (ACPP) (PAP/ACPP)
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse liver, Rat liver
Immunogen:A synthesized peptide derived from human Prostatic Acid Phosphatase (ACPP) (PAP/ACPP)
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:55
Uniprot:P15309
Calculated MW:50kDa
Observed MW:45KDa
UniProt Protein Function:ACPP: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.1.3.2; Cofactor and Vitamin Metabolism - riboflavin; Phosphatase; EC 3.1.3.5; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: multivesicular body; extracellular space; Golgi cisterna; apical part of cell; lysosomal membrane; plasma membrane; integral to membrane; vesicle membrane; intracellular; nucleus; secretory granule; filopodium

Molecular Function:5'-nucleotidase activity; choline binding; identical protein binding; acid phosphatase activity; protein homodimerization activity; phosphoric monoester hydrolase activity; thiamin phosphate phosphatase activity

Biological Process: thiamin metabolic process; dephosphorylation; positive regulation of adenosine receptor signaling pathway; nucleotide metabolic process; regulation of sensory perception of pain; adenosine metabolic process; purine base metabolic process

NCBI Summary:This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]
UniProt Code:P15309
NCBI GenInfo Identifier:130730
NCBI Gene ID:55
NCBI Accession:P15309.3
UniProt Related Accession:P15309
Molecular Weight:
NCBI Full Name:Prostatic acid phosphatase
NCBI Synonym Full Names:acid phosphatase, prostate
NCBI Official Symbol:ACPP  
NCBI Official Synonym Symbols:ACP3; 5'-NT; ACP-3  
NCBI Protein Information:prostatic acid phosphatase
UniProt Protein Name:Prostatic acid phosphatase
UniProt Synonym Protein Names:5'-nucleotidase (EC:3.1.3.5); 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase
UniProt Gene Name:ACPP  
UniProt Entry Name:PPAP_HUMAN

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