Anti-PRKG2 Antibody (CAB18575)
- SKU:
- CAB18575
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-PRKG2 Antibody |
| Antibody SKU: | CAB18575 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PRKG2. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Rat brain |
| Immunogen: | Recombinant protein of human PRKG2. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5593 |
| Uniprot: | Q13237 |
| Cellular Location: | Apical cell membrane, Lipid-anchor |
| Calculated MW: | 84kDa/87kDa |
| Observed MW: | 100kDa |
 | Western blot - PRKG2 Rabbit pAb (CAB18575) |
| Synonyms: | PRKGR2, cGK2, cGKII, PRKG2 |
| Background: | This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | PKG2: an AGC kinase of the PKG family. Type II cGMP-dependent protein kinase is expressed at high levels in brain, lung and intestinal mucosa. |
| UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, AGC; EC 2.7.11.12; Protein kinase, Ser/Thr (non-receptor); AGC group; PKG family Chromosomal Location of Human Ortholog: 4q13.1-q21.1 Cellular Component: apical plasma membrane; cytosol; nuclear membrane Molecular Function:ATP binding; cGMP binding; cGMP-dependent protein kinase activity; protein homodimerization activity; protein kinase activity Biological Process: blood coagulation; circadian regulation of gene expression; nitric oxide metabolic process; protein amino acid phosphorylation; regulation of nitric-oxide synthase activity; signal transduction |
| NCBI Summary: | This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q13237 |
| NCBI GenInfo Identifier: | 6226833 |
| NCBI Gene ID: | 5593 |
| NCBI Accession: | Q13237.1 |
| UniProt Secondary Accession: | Q13237,O00125, O60916, B4DMX3, E7EPE6, |
| UniProt Related Accession: | Q13237 |
| Molecular Weight: | 84,398 Da |
| NCBI Full Name: | cGMP-dependent protein kinase 2 |
| NCBI Synonym Full Names: | protein kinase, cGMP-dependent, type II |
| NCBI Official Symbol: | PRKG2 |
| NCBI Official Synonym Symbols: | cGK2; cGKII; PRKGR2 |
| NCBI Protein Information: | cGMP-dependent protein kinase 2 |
| UniProt Protein Name: | cGMP-dependent protein kinase 2 |
| UniProt Synonym Protein Names: | cGMP-dependent protein kinase II; cGKII |
| Protein Family: | cGMP-dependent protein kinase |
| UniProt Gene Name: | PRKG2 |
| UniProt Entry Name: | KGP2_HUMAN |