Anti-PRKACG Antibody (CAB7715)
- SKU:
- CAB7715
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PRKACG Antibody |
| Antibody SKU: | CAB7715 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human PRKACG (NP_002723.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human PRKACG (NP_002723.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGNA PAKK DTEQ EESV NEFL AKAR GDFL YRWG NPAQ NTAS SDQF ERLR TLGM GSFG RVML VRHQ ETGG HYAM KILN KQKV VKMK QVEH ILNE KRIL QAID FPFL VKLQ FSFK DNSY LYLV MEYV PGGE MFSR LQRV GRFS EPHA CFYA AQVV LAVQ YLHS LDLI HRDL KPEN LLID QQGY LQVT DFGF AKRV KGRT WTLC GTPE YLAP EIIL SKGY NKAV DWWA LGVL IYEM AVGF PPFY ADQP IQIY EKIV SGRV RFPS KLSS DLKH LLRS LLQV DLTK RFGN LRNG VGDI KNHK WFAT TSWI AIYE KKVE APFI PKYT GPGD ASNF DDYE EEEL RISI NEKC AKEF SEF |
| Gene ID: | 5568 |
| Uniprot: | P22612 |
| Cellular Location: | |
| Calculated MW: | 40kDa |
| Observed MW: | 42kDa |
| Synonyms: | PRKACG, BDPLT19, KAPG, PKACg |
| Background: | Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. |
| UniProt Protein Function: | PKACG: Phosphorylates a large number of substrates in the cytoplasm and the nucleus. A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript. Activated by cAMP. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. |
| UniProt Protein Details: | Protein type:Protein kinase, AGC; EC 2.7.11.11; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; PKA family Chromosomal Location of Human Ortholog: 9q13 Cellular Component: cytosol Molecular Function:cAMP-dependent protein kinase activity; ATP binding Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; male gonad development; glucose metabolic process; pathogenesis; signal transduction; protein amino acid phosphorylation; gluconeogenesis; phospholipase C activation; triacylglycerol catabolic process; carbohydrate metabolic process; energy reserve metabolic process; innate immune response; renal water homeostasis; spermatogenesis; blood coagulation; regulation of insulin secretion; transmembrane transport Disease: Mental Retardation, Autosomal Dominant 31 |
| NCBI Summary: | Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P22612 |
| NCBI GenInfo Identifier: | 207029159 |
| NCBI Gene ID: | 5568 |
| NCBI Accession: | NP_002723.2 |
| UniProt Secondary Accession: | P22612,O60850, Q5VZ02, Q86YI1, |
| UniProt Related Accession: | P22612 |
| Molecular Weight: | 65.0 kDa |
| NCBI Full Name: | Homo sapiens protein kinase, cAMP-dependent, catalytic, gamma (PRKACG), mRNA |
| NCBI Synonym Full Names: | protein kinase, cAMP-dependent, catalytic, gamma |
| NCBI Official Symbol: | PRKACG |
| NCBI Official Synonym Symbols: | KAPG; PKACg; BDPLT19 |
| NCBI Protein Information: | cAMP-dependent protein kinase catalytic subunit gamma |
| UniProt Protein Name: | cAMP-dependent protein kinase catalytic subunit gamma |
| Protein Family: | Protein lysine acetyltransferase |
| UniProt Gene Name: | PRKACG |
| UniProt Entry Name: | KAPCG_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PRKACG antibody (CAB7715) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of A549 cells using PRKACG antibody (CAB7715). Blue: DAPI for nuclear staining. |
Related Products
